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surgery of the primary tumour

PROCEDURE2 trials

Sponsors

Dutch Colorectal Cancer Group, State Scientific Centre of Coloproctology, Russian Federation

Conditions

Colon CancerColonic DiseaseColorectal NeoplasmsDigestive System DiseasesDigestive System NeoplasmsGastrointestinal DiseasesGastrointestinal NeoplasmsIntestinal Diseases

Phase 3

The Role of Surgery of the Primary Tumour in Patients With Synchronous Unresectable Metastases of Colorectal Cancer
CompletedNCT01606098
Dutch Colorectal Cancer GroupColon Cancer, Primary Tumour, Rectal Cancer
Start: 2012-07-31End: 2022-12-31Updated: 2023-09-13

Unknown Phase

Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases
NCT05322486
State Scientific Centre of Coloproctology, Russian FederationColonic Disease, Colorectal Neoplasms, Digestive System Diseases +10
Start: 2020-10-29End: 2022-12-31Target: 200Updated: 2022-04-11

Related Papers

Upfront resection versus no resection of the primary tumor in patients with synchronous metastatic colorectal cancer: the randomized phase III CAIRO4 study conducted by the Dutch Colorectal Cancer Group and the Danish Colorectal Cancer Group.
2024-06-079 citations
Upfront palliative resection of primary tumor versus no resection in patients with synchronous metastatic colorectal cancer: The randomized phase 3 CAIRO4 study of the Dutch Colorectal Cancer Group (DCCG).
Journal of Clinical Oncology2023-06-015 citations
Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment
JAMA Surgery2021-10-0951 citations
The Role of Primary Tumor Resection in Colorectal Cancer Patients with Asymptomatic, Synchronous, Unresectable Metastasis: A Multicenter Randomized Controlled Trial
Cancers2020-08-1656 citations
A randomized controlled trial comparing primary tumour resection plus chemotherapy with chemotherapy alone in incurable stage IV colorectal cancer: JCOG1007 (iPACS study)
Japanese Journal of Clinical Oncology2019-11-1944 citations
The CAIRO4 study: The role of surgery of the primary tumour with few or absent symptoms in patients with synchronous unresectable metastases of colorectal cancer—A randomized phase III study of the Dutch Colorectal Cancer Group (DCCG).
Journal of Clinical Oncology2016-02-012 citations
The CAIRO4 study: The role of surgery of the primary tumour with few or absent symptoms in patients with synchronous unresectable metastases of colorectal cancer—A randomized phase III study of the Dutch Colorectal Cancer Group (DCCG).
Journal of Clinical Oncology2015-05-206 citations
The CAIRO4 study: the role of surgery of the primary tumour with few or absent symptoms in patients with synchronous unresectable metastases of colorectal cancer--a randomized phase III study of the Dutch Colorectal Cancer Group (DCCG).
2014-10-0261 citations