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sulphonylurea

DRUG10 trials

Sponsors

GlaxoSmithKline, AstraZeneca, University of Manchester, Novo Nordisk A/S, Janssen Research & Development, LLC

Conditions

DiabetesDiabetes Mellitus, Type 2HypoglycemiaNon-Insulin-Dependent Diabetes MellitusType 2 DiabetesType 2 Diabetes Mellitus

Phase 3

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes
CompletedNCT00359112
GlaxoSmithKlineNon-Insulin-Dependent Diabetes Mellitus
Start: 2004-02-29Target: 544Updated: 2009-05-18
52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period
CompletedNCT00575588
AstraZenecaType 2 Diabetes
Start: 2007-12-31End: 2010-08-31Updated: 2012-03-21
Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 Diabetes
CompletedNCT00789191
Novo Nordisk A/SDiabetes, Diabetes Mellitus, Type 2
Start: 2008-11-30End: 2009-08-31Updated: 2017-03-14
The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)
CompletedNCT01137812
Janssen Research & Development, LLCDiabetes Mellitus, Type 2
Start: 2010-07-31End: 2012-03-31Updated: 2015-01-15
A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea
CompletedNCT01381900
Janssen Research & Development, LLCDiabetes Mellitus, Type 2
Start: 2011-08-31End: 2012-11-30Updated: 2014-05-09

Phase 4

Sitagliptin Versus Sulphonylurea in Type 2 Diabetes During Ramadan
TerminatedNCT00766441
University of ManchesterDiabetes, Hypoglycemia
Start: 2008-08-31End: 2009-10-31Updated: 2010-01-12
Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes
CompletedNCT01917656
Novo Nordisk A/SDiabetes, Diabetes Mellitus, Type 2
Start: 2014-01-09End: 2014-09-04Updated: 2017-08-24
Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy
CompletedNCT02027753
SanofiDiabetes Mellitus, Type 2
Start: 2013-12-31End: 2015-04-30Updated: 2015-08-27
Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes
CompletedNCT02730377
Novo Nordisk A/SDiabetes, Diabetes Mellitus, Type 2
Start: 2016-03-28End: 2019-08-12Updated: 2020-07-07

Unknown Phase

Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-402)
CompletedNCT01278485
Merck Sharp & Dohme LLCType 2 Diabetes Mellitus
Start: 2011-05-31End: 2012-06-30Updated: 2015-07-28

Related Papers

Maintenance of glycaemic control with liraglutide versus oral antidiabetic drugs as add‐on therapies in patients with type 2 diabetes uncontrolled with metformin alone: A randomized clinical trial in primary care ( <scp>LIRA‐PRIME</scp> )
Diabetes Obesity and Metabolism2021-10-0914 citations
922-P: LIRA-PRIME: A Randomized Trial in Primary Care Settings of Liraglutide vs. OAD for Glycemic Control in Patients with Type 2 Diabetes Not in Control on Metformin
Diabetes2020-06-011 citations
LIRA-PRIME Trial Design and Baseline Data—Efficacy in Controlling Glycemia with Liraglutide in a Primary Care Setting
Diabetes2018-06-22
Impact of Canagliflozin Treatment on Health-Related Quality of Life among People with Type 2 Diabetes Mellitus: A Pooled Analysis of Patient-Reported Outcomes from Randomized Controlled Trials
Patient2018-01-0810 citations
Vildagliptin has the same safety profile as a sulfonylurea on bone metabolism and bone mineral density in post-menopausal women with type 2 diabetes: a randomized controlled trial.
2017-05-1516 citations
Longer-term safety and tolerability of canagliflozin in patients with type 2 diabetes: a pooled analysis
Current Medical Research and Opinion2016-12-1932 citations
Canagliflozin provides greater attainment of both HbA1c and body weight reduction versus sitagliptin in patients with type 2 diabetes
Postgraduate Medicine2016-07-0814 citations
Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus from Latin America
Current Medical Research and Opinion2015-11-1810 citations
Diabetes-Related Composite Quality End Point Attainment: Canagliflozin Versus Sitagliptin Based on a Pooled Analysis of 2 Clinical Trials.
2015-03-189 citations
Saxagliptin Efficacy and Safety in Patients with Type 2 Diabetes Mellitus Stratified by Cardiovascular Disease History and Cardiovascular Risk Factors: Analysis of 3 Clinical Trials
Postgraduate Medicine2014-10-014 citations
Canagliflozin, a sodium glucose co-transporter 2 inhibitor, improves model-based indices of beta cell function in patients with type 2 diabetes.
2014-03-0193 citations
Saxagliptin versus glipizide as add-on therapy to metformin: assessment of hypoglycemia
Current Medical Research and Opinion2014-01-074 citations
How many unpublished studies? ClinicalTrials.gov (n = 2614 studies): diabetes | Closed Studies | Interventional Studies | Phase 3, 4 | Search Date: Oct 27, 2014
Figshare2014-01-01
Saxagliptin vs. glipizide as add-on therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: long-term (52-week) extension of a 52-week randomised controlled trial.
2013-04-0162 citations