FindTrial
Sign In

Sulphadoxine-pyrimethamine

DRUG15 trials

Sponsors

London School of Hygiene and Tropical Medicine, Ghana Health Services, Hospital Clinic of Barcelona, Ministry of Health and Medical Services, Solomon Islands, Institut Pasteur

Conditions

AnaemiaAnaemia in ChildrenBirth WeightHIVHIV InfectionHIV InfectionsMalariaMalaria in Pregnancy

Phase 1

A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients
CompletedNCT02524444
ORIYOMI OMOTOYOSI AKINYOTUMalaria in Pregnant HIV + Patients
Start: 2015-09-30End: 2016-08-31Updated: 2017-12-11
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
CompletedNCT02527005
University of IbadanHIV, Malaria, Pregnant
Start: 2015-09-30End: 2016-08-31Updated: 2017-12-11
Monthly Versus Two Doses of Ante-Natal Intermittent Preventive Treatment With Sulphadoxine-Pyrimethamine
NCT03599596
University College Hospital, IbadanMalaria
Start: 2018-09-01End: 2019-02-01Target: 136Updated: 2018-07-26

Phase 2

Effectiveness of Intermittent Preventive Treatment for Malaria in Children
CompletedNCT00119132
London School of Hygiene and Tropical MedicineMalaria
Start: 2005-06-30End: 2006-12-31Updated: 2017-01-12
Navrongo Drug Options for IPT in Pregnancy Trial
CompletedNCT00146783
London School of Hygiene and Tropical MedicineMalaria
Start: 2004-06-30End: 2007-02-28Updated: 2017-01-12
Kilimanjaro IPTi Drug Options Trial
CompletedNCT00158574
London School of Hygiene and Tropical MedicineMalaria
Start: 2005-01-31End: 2008-06-30Updated: 2017-01-12
Phase 2 Efficacy Study of Primaquine and Methylene Blue
CompletedNCT02831023
University of California, San FranciscoMalaria
Start: 2016-07-31End: 2017-01-31Updated: 2017-01-11

Phase 3

Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
CompletedNCT00131703
London School of Hygiene and Tropical MedicineMalaria, Pregnancy
Start: 2003-03-31End: 2005-03-31Target: 900Updated: 2025-03-04
Efficacy of Antifolates Against Malaria in HIV-infected Pregnant Women and the Emergence of Induced Resistance in Plasmodium Falciparum
CompletedNCT01746199
Institut PasteurHIV Infection, Malaria in Pregnancy
Start: 2013-12-31End: 2019-12-31Updated: 2020-11-30
Improving PRegnancy Outcomes With Intermittent preVEntive Treatment in Africa
CompletedNCT03208179
Liverpool School of Tropical MedicineMalaria, Malaria in Pregnancy, Pregnancy
Start: 2018-03-29End: 2020-03-15Updated: 2022-06-27

Phase 4

A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands
TerminatedNCT00964691
Ministry of Health and Medical Services, Solomon IslandsMalaria, Malaria in Pregnancy
Start: 2009-08-31End: 2010-08-31Target: 2504Updated: 2010-07-07

Unknown Phase

Relationships Between the Use of Antimalarial Drugs in Pregnancy and Plasmodium Falciparum Resistance
CompletedNCT00140517
London School of Hygiene and Tropical MedicineAnaemia, Birth Weight, Malaria in Pregnancy
Start: 2002-10-31End: 2008-03-31Target: 700Updated: 2017-01-12
Study on Preventing Anemia in Children in Ghana
CompletedNCT00301054
Ghana Health ServicesAnaemia in Children
Start: 2005-06-30End: 2006-04-30Target: 872Updated: 2006-05-29
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
CompletedNCT00811421
Hospital Clinic of BarcelonaHIV Infections, Malaria, Pregnancy
Start: 2009-09-30End: 2013-12-31Updated: 2014-03-20
Efficacy of Sulphadoxine-Pyrimethamine versus Dihydroartemisinin-Piperaquine for Intermittent Preventive Therapy of Pregnancy-associated Malaria
Active, not recruitingPACTR201701001982152
Babcock UniversityMalaria
Start: 2018-04-01Target: 350Updated: 2026-01-27

Related Papers

Prevalence and risk factors of curable sexually transmitted and reproductive tract infections and malaria co-infection among pregnant women at antenatal care booking in Kenya, Malawi and Tanzania: a cross-sectional study of randomised controlled trial data
BMJ Public Health2024-09-012 citations
Intermittent preventive treatment with sulphadoxine-pyrimethamine but not dihydroartemisinin-piperaquine modulates the relationship between inflammatory markers and adverse pregnancy outcomes in Malawi
PLOS Global Public Health2024-05-167 citations
Effect of monthly intermittent preventive treatment with dihydroartemisinin-piperaquine with and without azithromycin versus monthly sulfadoxine-pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial.
2023-03-1058 citations
Weight change during the first week of life and a new method for retrospective prediction of birthweight among exclusively breastfed newborns
Acta Obstetricia Et Gynecologica Scandinavica2022-02-135 citations
The Effects of Malaria in Pregnancy on Neurocognitive Development in Children at 1 and 6 Years of Age in Benin: A Prospective Mother–Child Cohort
Clinical Infectious Diseases2021-06-1828 citations
Birth weight, growth, nutritional status and mortality of infants from Lambaréné and Fougamou in Gabon in their first year of life
PLoS ONE2021-02-0924 citations
Comparative study of mefloquine and sulphadoxine–pyrimethamine for malaria prevention among pregnant women with <scp>HIV</scp> in southwest Nigeria
International Journal of Gynecology & Obstetrics2018-05-028 citations
A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model
eLife2018-02-2667 citations
Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.
2018-02-0681 citations
Resisting and tolerating P. falciparum in pregnancy under different malaria transmission intensities
BMC Medicine2017-07-0412 citations
Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
BMJ Open2016-06-01105 citations
Mortality, Morbidity, and Developmental Outcomes in Infants Born to Women Who Received Either Mefloquine or Sulfadoxine-Pyrimethamine as Intermittent Preventive Treatment of Malaria in Pregnancy: A Cohort Study
PLoS Medicine2016-02-2326 citations
Effectiveness of two antifolate prophylactic strategies against malaria in HIV-positive pregnant women in Bangui, Central African Republic: study protocol for a randomized controlled trial (MACOMBA).
2013-08-142 citations
Intermittent preventive treatment with sulfadoxine-pyrimethamine versus weekly chloroquine prophylaxis for malaria in pregnancy in Honiara, Solomon Islands: a randomised trial
PubMed2013-06-294 citations
Coverage, adherence and costs of intermittent preventive treatment of malaria in children employing different delivery strategies in Jasikan, Ghana.
2011-11-0322 citations
Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.
2010-03-0123 citations
Options for the delivery of intermittent preventive treatment for malaria to children: a community randomised trial.
2009-09-3036 citations
Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial.
2009-09-1683 citations
High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581.
2009-02-24132 citations
Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial.
2008-12-2288 citations

1 more papers not shown