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Sulodexide

DRUG16 trials

Sponsors

Keryx Biopharmaceuticals, University of Iowa, Corbridge Group Philippines, Inc., Ajou University School of Medicine, Bama GeVe, S.L.U.

Conditions

AnticoagulantCOVID-19Chronic Kidney DiseaseCovid19Dense Deposit DiseaseDiabetic NephropathyDiabetic Nephropathy Type 2Diabetic Retinopathy

Phase 1

Sulodexide Treatment in Patients With Dense Deposit Disease
WithdrawnNCT00583427
University of IowaDense Deposit Disease
Start: 2007-12-31End: 2009-12-31Updated: 2015-06-11

Phase 2

Diabetic Retinopathy Sulodexide Study
CompletedNCT01295775
Ajou University School of MedicineDiabetic Retinopathy
Start: 2009-02-28End: 2011-05-31Updated: 2012-11-06
Sulodexide Efficacy in Chronic Idiopathic Subjective Tinnitus
CompletedNCT02737670
St Joseph University, Beirut, LebanonTinnitus, Subjective
Start: 2014-08-31End: 2017-08-31Updated: 2017-09-14
Suloexide in the Treatment of Early Stages of COVID-19
CompletedNCT04483830
ClinedemCovid19
Start: 2020-06-05End: 2020-09-07Updated: 2020-09-09

Phase 3

Effect of Sulodexide in Early Diabetic Nephropathy
CompletedNCT00130208
Keryx BiopharmaceuticalsDiabetic Nephropathy
Start: 2005-08-31End: 2008-02-29Updated: 2018-03-23
Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong
TerminatedNCT00462202
Keryx BiopharmaceuticalsDiabetic Nephropathy
Start: 2007-04-30End: 2008-03-31Updated: 2017-03-03
The Efficacy and Safety Study of Sulodexide in Filipino Diabetic Patients With Chronic Kidney Disease
NCT01000545
Corbridge Group Philippines, Inc.Chronic Kidney Disease
Start: 2009-11-30End: 2012-12-31Target: 1508Updated: 2009-10-30
Endothelial Function Evaluation in Patients With PAOD Treated With Sulodexide + Conventional Treatment (CT) Vs CT Alone
NCT03370705
Alfa Wassermann TunisiaPeripheral Arterial Obstructive Disease
Start: 2019-01-31End: 2020-03-30Target: 156Updated: 2019-12-02
Sulodexide, VESSEL®, for the Prevention of Recurrent Venous Thromboembolism (The Jason Study)
RecruitingNCT04257487
Arianna Anticoagulazione FoundationAnticoagulant, Elderly, Venous Thromboembolism
Start: 2020-12-21End: 2027-01-02Target: 1455Updated: 2024-07-31
Endothelial Protection in Post COVID-19 Patients With Sulodexide
CompletedNCT05371925
Centro Medico del NoroesteEndothelial Dysfunction, Post COVID-19, Thrombosis
Start: 2023-06-01End: 2024-04-19Updated: 2024-08-09
Sulodexide in Controlling the Recurrence of Psoriasis
Enrolling by invitationNCT06982196
Xijing HospitalPsoriasis (PsO), Randomised Controlled Trial
Start: 2025-04-20End: 2027-12-31Target: 160Updated: 2025-05-21

Phase 4

Effect of Sulodexide in Overt Diabetic Nephropathy
TerminatedNCT00130312
Keryx BiopharmaceuticalsDiabetic Nephropathy
Start: 2005-08-31End: 2008-03-31Updated: 2021-03-19
Prospective Evaluation of the QoL of Patients With PTS Who Receive Compression Therapy and Sulodexide
TerminatedNCT02512601
Bama GeVe, S.L.U.Post-thrombotic Syndrome
Start: 2015-09-30End: 2017-02-28Updated: 2017-08-31
Rotation for Optimal Targeting of Albuminuria and Treatment Evaluation (ROTATE-2)
WithdrawnNCT03504566
Steno Diabetes Center CopenhagenDiabetic Nephropathy Type 2
Start: 2017-11-15End: 2019-06-01Updated: 2018-09-14
Endothelial Protection in Convalescent COVID-19 Patients
TerminatedNCT05252923
Pirogov Russian National Research Medical UniversityCOVID-19, Endothelial Dysfunction, Inflammation +1
Start: 2022-04-01End: 2022-12-31Updated: 2025-06-13

Unknown Phase

The Study of Reducing Adverse Effects After Radiofrequency Ablation Combined With Sclerotherapy
NCT05654233
Chengdu University of Traditional Chinese MedicineVaricose Veins of Lower Limb, Vascular Diseases, Peripheral, Venous Insufficiency of Leg
Start: 2023-02-01End: 2023-09-01Target: 120Updated: 2023-01-03

Related Papers

Design and rationale of a randomized, placebo-controlled trial on the efficacy and safety of sulodexide for extended treatment in elderly patients after a first venous thromboembolism.
2020-05-254 citations
Effect of sulodexide in patients with non-proliferative diabetic retinopathy: diabetic retinopathy sulodexide study (DRESS)
Graefe s Archive for Clinical and Experimental Ophthalmology2014-08-1119 citations
Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus.
2010-09-25273 citations