Sulfamethoxazole

DRUG10 trials

Sponsors

Hansa Biopharma AB, The University Of Queensland, Friedrich-Schiller-Universitaet Jena, Lederle Laboratories, U.S. Bioscience

Conditions

Anti-GBM antibody disease (Goodpasture disease)BronchitisDiabetes Mellitus, Insulin-DependentHIV InfectionsHypotonia Cystinuria SyndromeInfectious endocarditis caused by Gram-positive cocci (staphylococciIsolated PREPL DeficiencyMycobacterium abscessus pulmonary disease

Phase 1

Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

CompletedNCT00002120

U.S. BioscienceHIV Infections, Pneumonia, Pneumocystis Carinii

Target: 20Updated: 2005-06-24

Phase 2

Islet Transplantation for Type 1 Diabetes

CompletedNCT00014911

National Institute of Allergy and Infectious Diseases (NIAID)Diabetes Mellitus, Insulin-Dependent

Start: 2001-04-30End: 2010-08-31Updated: 2017-03-15

Sulfamethoxazole for the Treatment of Primary PREPL Deficiency

Universitair Ziekenhuis BrusselHypotonia Cystinuria Syndrome, Isolated PREPL Deficiency

Start: 2015-10-31End: 2016-10-31Target: 15Updated: 2015-12-29

Finding the Optimal Regimen for Mycobacterium abscessus Treatment

RecruitingCTIS2023-506575-99-00

The University Of QueenslandMycobacterium abscessus pulmonary disease

Start: 2023-01-02Target: 20Updated: 2025-10-13

Phase 3

A Phase 3 open-label, controlled, randomised, multi-centre trial comparing imlifidase and standard-of-care with standard-of-care alone in the treatment of severe anti-GBM antibody disease (Goodpasture disease)

Active, not recruitingCTIS2022-500121-33-01

Hansa Biopharma ABAnti-GBM antibody disease (Goodpasture disease)

Start: 2023-05-08Target: 35Updated: 2024-12-19

Efficacy and safety of Dalbavancin in the treatment of infective Endocarditis caused by gram-positive cocci

Not yet recruitingCTIS2026-526149-91-00

Friedrich-Schiller-Universitaet Jenaenterococci, Infectious endocarditis caused by Gram-positive cocci (staphylococci, streptococci)

Target: 166Updated: 2026-06-30

Unknown Phase

A Comparison of Dapsone and Trimethoprim-Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

CompletedNCT00002283

Jacobus PharmaceuticalHIV Infections, Pneumonia, Pneumocystis Carinii

Updated: 2005-06-24

A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome

CompletedNCT00002002

Lederle LaboratoriesHIV Infections, Pneumonia, Pneumocystis Carinii

Updated: 2005-06-24

A Safety Study of Balsamic Bactrim in Pediatric Participants With Acute Bronchitis

CompletedNCT02879981

Hoffmann-La RocheBronchitis

Start: 2016-11-10End: 2017-08-28Updated: 2019-12-13

A Non-Interventional Safety Study of Balsamic Bactrim

CompletedNCT02902640

Hoffmann-La RocheBronchitis

Start: 2016-11-15End: 2017-07-31Updated: 2017-11-07

Related Papers

A pilot study of safety of sulfamethoxazole, trimethoprim and guaifenesin in pediatric and adult patients with acute bronchitis

BMC Research Notes2019-03-041 citations

Insulin-mimetic effects of short-term rapamycin in type 1 diabetic patients prior to islet transplantation.

2018-04-136 citations

International trial of the Edmonton protocol for islet transplantation.

2006-09-011367 citations