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Sublingual Immunotherapy

DRUG13 trials

Sponsors

ALK-Abelló A/S, University of North Carolina, Chapel Hill, HAL Allergy, University of Genova, Stanford University

Conditions

Allergic RhinitisAllergic Rhinitis (w/w Asthma) Due to Alternaria AlternataAllergiesAllergyAsthmaAsthma.Birch Pollen AllergyBronchial asthma

Phase 1

Sublingual Immunotherapy Studies for Grass and Dust Mite Allergies
CompletedNCT01529437
Stanford UniversityAllergic Rhinitis, Allergies, Asthma
Start: 2005-01-31End: 2014-01-31Updated: 2015-11-26

Phase 2

SUBLIVAC® Birch PROBE Study
CompletedNCT00932607
HAL AllergyBirch Pollen Allergy, Seasonal Rhinitis and/or Rhinoconjunctivitis
Start: 2009-07-31Updated: 2012-02-07
Efficacy of VALERGEN-BT sublingual vaccine in asthmatic adults.
Active, not recruitingRPCEC00000029
National Biopreparations Center (BIOCEN)Asthma
Start: 2005-09-07Updated: 2026-10-05
Efficacy of VALERGEN-DS sublingual vaccine in asthmatic adults
Active, not recruitingRPCEC00000030
National Biopreparations Center (BIOCEN)Bronchial asthma.
Start: 2005-09-07Updated: 2026-10-05
Efficacy of VALERGEN-DP sublingual vaccine in asthmatic adults.
Active, not recruitingRPCEC00000034
National Biopreparations Center (BIOCEN)Bronchial asthma
Start: 2005-09-07Updated: 2026-10-05
Combined sublingual immunotherapy VALERGEN-DP and VALERGEN-BT-Asthma-Adults-Phase II
RecruitingRPCEC00000240
National Center of Bioproducts (BIOCEN)Asthma
Start: 2019-02-07Target: 120Updated: 2026-10-05
VALERGEN-combination of routes- Asthma-Adults-Phase II
Active, not recruitingRPCEC00000298
National Center of Bioproducts (BioCen)Asthma
Start: 2020-07-01Target: 180Updated: 2026-10-05

Phase 3

Efficacy and Safety Trial of SLITone(TM) Birch in Subjects With Hayfever
CompletedNCT00310466
ALK-Abelló A/SAllergy
Start: 2005-06-30End: 2007-01-31Updated: 2013-05-14
Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy
CompletedNCT04813380
Zagazig UniversityEffects of Immunotherapy
Start: 2021-07-27End: 2022-10-10Updated: 2022-12-20
Effect of Sublingual Immunotherapy on Platlet factor4 Level in Children
NCT04851860
Zagazig UniversityAllergic Rhinitis
Start: 2021-04-12End: 2021-11-20Target: 30Updated: 2021-04-21

Phase 4

Sublingual Immunotherapy In Alternaria-Induced Rhinitis
CompletedNCT01127035
University of GenovaAllergic Rhinitis (w/w Asthma) Due to Alternaria Alternata
Start: 2006-01-31End: 2008-10-31Updated: 2010-06-07
Pharmacovigilance-VALERGEN-Asthma
Active, not recruitingRPCEC00000231
National Center of Bioproducts (BIOCEN)Asthma.
Start: 2011-02-01Target: 2108Updated: 2026-10-05

Unknown Phase

Immunotherapy for Peanut Allergy
CompletedNCT00429429
University of North Carolina, Chapel HillAllergy
Start: 2006-04-30End: 2011-05-31Updated: 2016-06-20