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Structured treatment interruption

BEHAVIORAL7 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), University of North Carolina, Chapel Hill, The Wistar Institute, French National Agency for Research on AIDS and Viral Hepatitis, ANRS, Emerging Infectious Diseases

Conditions

HIVHIV Infections

Phase 1

Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV
CompletedNCT00842634
University of PennsylvaniaHIV, HIV Infections
Start: 2009-01-31End: 2013-01-31Updated: 2019-02-08

Phase 2

Effects of Immunization With HIV-1 Immunogen Plus Anti-HIV Treatment Interruption on the Levels of HIV
WithdrawnNCT00021762
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections
Updated: 2021-11-01
Early and Intermittent Antiretroviral Therapy in Naive HIV Infected Adults
CompletedNCT00820118
ANRS, Emerging Infectious DiseasesHIV Infections
Start: 2009-05-31End: 2012-05-31Updated: 2012-05-23

Phase 3

Randomised Trial of Structured Treatment Interruption of HAART in HIV-Infected Adults in Abidjan (ANRS 1269 TRIVACAN)
CompletedNCT00158405
French National Agency for Research on AIDS and Viral HepatitisHIV Infections
Start: 2002-12-31End: 2006-12-31Updated: 2008-12-30

Unknown Phase

Treatment Plan to Decrease Drug Exposure in HIV Infected Adolescents
WithdrawnNCT00067574
University of North Carolina, Chapel HillHIV Infections
Start: 2003-07-31Updated: 2017-03-06
Anti-HIV Medications and Structured Treatment Interruptions for People Recently Infected With HIV
WithdrawnNCT00084032
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections
Updated: 2012-10-29
Anti-HIV Treatment Interruptions in HIV Infected Adults in South Africa
CompletedNCT00100646
The Wistar InstituteHIV Infections
Start: 2007-03-31End: 2010-03-31Updated: 2014-08-27

Related Papers

Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells
Molecular Therapy — Methods & Clinical Development2016-01-01108 citations
Gene Editing of <i>CCR5</i> in Autologous CD4 T Cells of Persons Infected with HIV
New England Journal of Medicine2014-03-051333 citations
Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.
2011-06-287 citations