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Structured Lifestyle Intervention

BEHAVIORAL5 trials

Sponsors

Wake Forest University Health Sciences, National University of Singapore, Yunlong Wang, Texas Tech University

Conditions

AddictionAlzheimer DiseaseAtrial FibrillationBrain DiseasesCardiometabolic Health IndicatorsCatheter AblationCentral Nervous System DiseasesCognition Disorder

Phase 4

Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF
Not yet recruitingNCT07630454
Yunlong WangAtrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFpEF), Tirzepatide
Start: 2026-08-01End: 2029-12-01Target: 602Updated: 2026-06-05
Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients
Not yet recruitingNCT07715929
Yunlong WangAtrial Fibrillation, Catheter Ablation, Obesity & Overweight
Start: 2026-09-01End: 2029-12-30Target: 710Updated: 2026-07-21

Unknown Phase

U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk
CompletedNCT03688126
Wake Forest University Health SciencesAlzheimer Disease
Start: 2019-01-08End: 2025-05-16Updated: 2025-11-03
The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study
CompletedNCT05007353
National University of SingaporeAlzheimer Disease, Brain Diseases, Central Nervous System Diseases +7
Start: 2021-08-23End: 2025-12-29Updated: 2026-08-10
Tirzepatide Impact Assessment Study
RecruitingNCT07740291
Texas Tech UniversityAddiction, Cardiometabolic Health Indicators, Eating Disorders +2
Start: 2025-01-02End: 2026-12-07Target: 27Updated: 2026-07-31

Related Papers

Age, Multidomain Lifestyle Intervention, and White Matter Integrity
JAMA Network Open2026-07-13
Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention
JAMA Neurology2026-04-20
Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function
JAMA2025-07-2869 citations
Baseline cognition and demographic, lifestyle, and cardiovascular risk factors in US POINTER
Alzheimer s & Dementia2025-07-013 citations
Subjective cognitive decline among diverse older adults: Prevalence and associations with objective cognition
Alzheimer s & Dementia2025-06-262 citations
Associations Between Deficit Accumulation Frailty and Baseline Markers of Lifestyle in the U.S. POINTER Trial
The Journals of Gerontology Series A2024-11-16
Study design and methods: U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER)
Alzheimer s & Dementia2023-09-3067 citations