streptomycin

DRUG5 trials

Sponsors

FDA Office of Orphan Products Development, National Jewish Health, Centers for Disease Control and Prevention, Maimónides Biomedical Research Institute of Córdoba, University of Oxford

Conditions

Mycobacterium Avium-intracellulare InfectionPatients Colonized by Klebsiella Pneumoniae.PlaguePlague, BubonicPlague, PneumonicTuberculosis, Pulmonary

Phase 2

Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease

CompletedNCT00004689

National Jewish HealthMycobacterium Avium-intracellulare Infection

Start: 1991-01-31End: 1998-09-30Target: 50Updated: 2015-03-25

Treatment and Diagnosis of Plague

CompletedNCT00128466

Centers for Disease Control and PreventionPlague

Start: 2004-08-31End: 2007-02-28Updated: 2009-02-26

Phase 3

Ciprofloxacin Versus an Aminoglycoside Followed by Ciprofloxacin for Bubonic Plague

CompletedNCT04110340

University of OxfordPlague, Bubonic, Plague, Pneumonic

Start: 2020-02-15End: 2025-02-05Updated: 2025-03-06

Unknown Phase

Pilot Randomized Study of Paromomycin (Aminosidine) vs Streptomycin for Uncomplicated Pulmonary Tuberculosis

CompletedNCT00004444

FDA Office of Orphan Products DevelopmentTuberculosis, Pulmonary

Start: 1994-11-30End: 2001-01-31Target: 24Updated: 2015-03-25

Efficacy of Intestinal Decontamination in Patients Colonized by Carbapenem-resistant Klebsiella Pneumoniae and Colistin

CompletedNCT02604849

Maimónides Biomedical Research Institute of CórdobaPatients Colonized by Klebsiella Pneumoniae.

Start: 2012-07-31End: 2015-11-30Updated: 2015-11-13

Related Papers

Performance of diagnostic procedures for bubonic plague in endemic settings in Madagascar: a prospective test accuracy sub-study within the IMASOY trial.

2025-12-11

Ciprofloxacin versus Aminoglycoside–Ciprofloxacin for Bubonic Plague

New England Journal of Medicine2025-08-062 citations

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus an aminoglycoside + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial-an update to the published protocol.

2024-07-051 citations

An open-label, randomized, non-inferiority trial of the efficacy and safety of ciprofloxacin versus streptomycin + ciprofloxacin in the treatment of bubonic plague (IMASOY): study protocol for a randomized control trial.

2020-08-1712 citations

Oral decontamination with aminoglycosides is associated with lower risk of mortality and infections in high-risk patients colonized with colistin-resistant, KPC-producing Klebsiella pneumoniae.

2016-07-2633 citations