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Stereotactic Radiation

RADIATION11 trials

Sponsors

Beth Israel Deaconess Medical Center, Wake Forest University Health Sciences, Washington University School of Medicine, University Health Network, Toronto, University of Florida

Conditions

AGuIXBrain CancerBrain MetastasesBrain TumorBreast CancerCarcinoma, HepatocellularColorectal CancerCystic

Phase 1

Stereotactic Body Radiotherapy for Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma
CompletedNCT01668134
Washington University School of MedicineCarcinoma, Hepatocellular, Intrahepatic Cholangiocarcinoma
Start: 2009-12-16End: 2015-12-22Updated: 2017-02-20
Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
CompletedNCT02052648
NewLink Genetics CorporationGlioblastoma Multiforme, Glioma, Gliosarcoma +1
Start: 2014-03-31End: 2019-06-20Updated: 2024-03-27
Safety Study of SBRT and Docetaxel for Locally Recurrent or Second Primary Squamous Cell Carcinoma of the Head and Neck
TerminatedNCT02110992
University of CincinnatiHead and Neck Cancer
Start: 2014-04-30End: 2017-03-29Updated: 2019-11-25
Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA
Active, not recruitingNCT02685332
University of Texas Southwestern Medical CenterEarly Stage Breast Cancer
Start: 2016-03-31End: 2027-08-01Updated: 2026-08-27
Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases
RecruitingNCT06238921
H. Lee Moffitt Cancer Center and Research InstituteBreast Cancer, Triple Negative Breast Cancer
Start: 2024-12-19End: 2027-02-28Target: 31Updated: 2025-12-05

Phase 2

Stereotactic Radiotherapy (SBRT) of Lung Metastasis
RecruitingNCT01803542
University Health Network, TorontoMetastasis From Other Cancers, Non-small Cell Lung Cancer
Start: 2006-03-01End: 2027-09-01Target: 200Updated: 2026-03-06
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
RecruitingNCT04899908
Brigham and Women's HospitalAGuIX, Brain Cancer, Brain Metastases +13
Start: 2021-09-15End: 2029-05-01Target: 134Updated: 2026-09-09

Unknown Phase

CyberKnife for Unresectable Renal Tumors
CompletedNCT00807339
Beth Israel Deaconess Medical CenterRenal Cancer
Start: 2006-03-31End: 2014-08-20Updated: 2017-03-21
Stereotactic Radiation to Decrease Pancreatic Secretions
CompletedNCT01656486
Wake Forest University Health SciencesPancreatic Fistulae
Start: 2012-07-31End: 2012-11-30Updated: 2022-06-10
Radiotherapy for Oligometastatic Prostate Cancer
CompletedNCT01859221
University of FloridaOligometastatic Prostate Cancer
Start: 2013-05-31End: 2022-09-13Updated: 2022-09-14
Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases
Active, not recruitingNCT03391362
Brigham and Women's HospitalBrain Metastases, Small Cell Lung Cancer
Start: 2018-02-23End: 2027-07-01Updated: 2026-07-14

Related Papers

Stereotactic Radiosurgery in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases: A Multi-Institutional, Phase II, Prospective Clinical Trial
Journal of Clinical Oncology2025-07-119 citations
Stereotactic radiosurgery in patients with small cell lung cancer and 1-10 brain metastases: A multi-institutional, phase II, prospective clinical trial.
Journal of Clinical Oncology2024-06-016 citations
Phase I/II study of stereotactic radiation and sacituzumab govitecan with zimberelimab in the management of metastatic triple negative breast cancer with brain metastases.
Journal of Clinical Oncology2024-06-011 citations
Quantifying gadolinium-based nanoparticle uptake distributions in brain metastases via magnetic resonance imaging.
2024-05-2513 citations
Combined cytotoxic and immune-stimulatory gene therapy using Ad-TK and Ad-Flt3L: Translational developments from rodents to glioma patients.
2023-08-1214 citations
Phase I/II study testing the combination of AGuIX nanoparticles with radiochemotherapy and concomitant temozolomide in patients with newly diagnosed glioblastoma (NANO-GBM trial protocol)
BMC Cancer2023-04-1549 citations
Single fraction ablative preoperative radiation treatment for early-stage breast cancer: the CRYSTAL study – a phase I/II clinical trial protocol
BMC Cancer2022-04-0217 citations
IMCT-21UPDATES ON PHASE 1B/2 COMBINATION STUDY OF THE IDO PATHWAY IHIBITOR INDOXIMOD WITH TEMOZOLOMIDE FOR ADULT PATIENTS WITH TEMOZOLOMIDE-REFRACTORY PRIMARY MALIGNANT BRAIN TUMORS
Neuro-Oncology2015-11-017 citations
OLIGOPELVIS – GETUG P07: a multicentre phase II trial of combined salvage radiotherapy and hormone therapy in oligometastatic pelvic node relapses of prostate cancer
BMC Cancer2015-09-2545 citations
A phase 1b/2 study of the combination of the IDO pathway inhibitor indoximod and temozolomide for adult patients with temozolomide-refractory primary malignant brain tumors: Safety analysis and preliminary efficacy of the phase 1b component.
Journal of Clinical Oncology2015-05-2013 citations
A phase I/II study of the combination of indoximod and temozolomide for adult patients with temozolomide-refractory primary malignant brain tumors.
Journal of Clinical Oncology2014-05-2020 citations