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Stereotactic Ablative Radiotherapy (SABR)

RADIATION17 trials

Sponsors

University of Louisville, University Medical Center Groningen, Luhua Wang, The Leeds Teaching Hospitals NHS Trust, London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Conditions

CardiacCardiac ArrhythmiaColorectal CancerEmphysemaHepatocellular Carcinoma(HCC)Kidney CancerMetastatic CancerMetastatic Colorectal Cancer

Phase 1

The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in Oligometastatic Gastrointestinal Cancer
NCT04625894
Fudan UniversityOligometastatic Gastrointestinal Cancer
Start: 2020-12-31End: 2023-06-30Target: 21Updated: 2020-11-12
Phase I/II Randomized Study of Stereotactic Ablative Radiotherapy (SABR) Versus Standard of Care for Refractory Structural Cardiac Arrhythmias (SABR-HEART)
WithdrawnNCT05084391
M.D. Anderson Cancer CenterCardiac, Cardiac Arrhythmia, Ventricular Tachyarrhythmias
Start: 2019-09-12End: 2024-02-08Updated: 2024-02-13

Phase 2

Safety of Pentoxifylline and Vitamin E With Stereotactic Ablative Radiotherapy (SABR) in Non-small Cell Lung Cancers
RecruitingNCT01871454
University of LouisvilleNon-small Cell Lung Cancers
Start: 2013-10-31End: 2025-12-31Target: 59Updated: 2024-02-07
Study of Stereotactic Ablative Radiotherapy (SABR) in Elderly Stage I NSCLC
NCT02584699
Luhua WangNon-Small Cell Lung Cancer
Start: 2015-07-31End: 2018-07-31Target: 40Updated: 2015-10-23
RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers
CompletedNCT04037358
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsProstate Cancer
Start: 2019-08-09End: 2025-07-15Updated: 2025-12-19
The Combination of Immunotherapy and Stereotactic Ablative Radiotherapy in MSS Oligometastatic Colorectal Cancer
NCT04535024
Fudan UniversityColorectal Cancer
Start: 2021-03-04End: 2022-12-31Target: 60Updated: 2021-05-11
The Combination of Fruquintinib, Tislelizumab and Stereotactic Ablative Radiotherapy in Metastatic Colorectal Cancer(RIFLE)
NCT04948034
Fudan UniversityMetastatic Colorectal Cancer
Start: 2021-08-23End: 2023-12-31Target: 68Updated: 2021-08-27

Unknown Phase

SABR-SCAN Trial for Pulmonary Oligometastases
CompletedNCT02414334
University Medical Center GroningenOligometastases
Start: 2015-06-30End: 2019-06-30Updated: 2024-03-01
A Study to Determine the Feasibility and Acceptability of Conducting a Phase III Randomised Controlled Trial Comparing Stereotactic Ablative Radiotherapy With Surgery in paTients With Peripheral Stage I nOn-small Cell Lung Cancer cOnsidered Higher Risk of Complications From Surgical Resection
CompletedNCT02629458
The Leeds Teaching Hospitals NHS TrustOncology
Start: 2015-07-01End: 2017-01-31Updated: 2019-07-12
Stereotactic Radiotherapy for Oligo-Progressive Metastatic Cancer (The STOP Trial)
Active, not recruitingNCT02756793
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sMetastatic Cancer
Start: 2016-10-31End: 2026-06-30Updated: 2025-12-31
CROSSFIRE Trial: Comparing the Efficacy of Irreversible Electroporation With Radiotherapy
CompletedNCT02791503
Dr. M.R. MeijerinkPancreatic Neoplasm
Start: 2016-05-30End: 2022-09-30Updated: 2022-12-20
Comparing Re-TACE Versus SABR for Post-prior-TACE Incompletely Regressed HCC: a Randomized Controlled Trial (TASABR)
NCT02921139
Dalin Tzu Chi General HospitalHepatocellular Carcinoma(HCC)
Start: 2016-11-30End: 2022-11-30Target: 120Updated: 2021-08-30
Stereotactic Ablative Radiotherapy for Refractory Ventricular Tachycardia
CompletedNCT03349892
University of California, Los AngelesRefractory Ventricular Tachycardia
Start: 2017-04-01End: 2019-08-06Updated: 2021-11-15
A Dose-escalation Trial of Stereotactic Ablative Body Radiotherapy for Non-spine Bone & Lymph Node Oligometastates
CompletedNCT03486431
Cancer Research AntwerpMetastatic Cancer
Start: 2017-07-05End: 2019-12-31Updated: 2024-02-08
Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy
CompletedNCT03673176
Stanford UniversityEmphysema
Start: 2013-02-11End: 2021-08-02Updated: 2024-07-11
A Prospective Registry Study of Stereotactic Ablative Radiotherapy (SABR) for Oligometastatic/Oligometastatic Renal Cell Carcinoma
Not yet recruitingNCT06585878
Cancer Institute and Hospital, Chinese Academy of Medical SciencesKidney Cancer, RCC, Renal Cell Carcinoma
Start: 2024-09-01End: 2027-04-30Target: 60Updated: 2024-09-19
Stereotactic Radiotherapy Versus Palliative Conventional Radiotherapy for Oligoprogressive Metastatic Cancers
RecruitingNCT06918951
British Columbia Cancer AgencyOligometastatic Disease, Oligoprogression, OligoProgressive Metastatic Disease
Start: 2025-12-04End: 2033-06-01Target: 194Updated: 2025-12-15

Related Papers

Systemic immunomodulation by irreversible electroporation versus stereotactic ablative body radiotherapy in locally advanced pancreatic cancer: the CROSSFIRE trial
Journal for ImmunoTherapy of Cancer2025-03-015 citations
Stereotactic Ablative Radiation for Oligoprogressive Cancers: Results of the Randomized Phase 2 STOP Trial.
2024-08-1925 citations
Stereotactic ablative radiotherapy combined with fruquintinib and tislelizumab in metastatic colorectal cancer: Updated findings from a single-arm, prospective phase II trial (RIFLE).
Journal of Clinical Oncology2024-06-011 citations
MRI-guided stereotactic ablative body radiotherapy versus CT-guided percutaneous irreversible electroporation for locally advanced pancreatic cancer (CROSSFIRE): a single-centre, open-label, randomised phase 2 trial.
2024-03-1926 citations
Protocol for the Veterans Affairs Cooperative Studies Program Study Number 2005
CHEST Pulmonary2023-10-057 citations
A phase II randomized trial of metastasis-directed therapy with alpha emitter radium-223 in men with oligometastatic castration-resistant prostate cancer (MEDAL).
2023-03-064 citations
RIFLE: a Phase II trial of stereotactic ablative radiotherapy combined with fruquintinib and tislelizumab in metastatic colorectal cancer
Gastroenterology report2022-12-308 citations
Radiofrequency ablation and chemotherapy versus chemotherapy alone for locally advanced pancreatic cancer (PELICAN): study protocol for a randomized controlled trial.
2021-04-2916 citations
Stereotactic radiotherapy for oligoprogressive ER-positive breast cancer (AVATAR)
BMC Cancer2021-03-2320 citations
Stereotactic Ablative Radiation Therapy to All Lesions in Patients With Oligometastatic Cancers: A Phase 1 Dose-Escalation Trial.
2020-12-088 citations
STRA-MI-VT (STereotactic RadioAblation by Multimodal Imaging for Ventricular Tachycardia): rationale and design of an Italian experimental prospective study.
2020-08-2715 citations
A phase II randomized trial of RAdium-223 dichloride and SABR Versus SABR for oligomEtastatic prostate caNcerS (RAVENS)
BMC Cancer2020-06-0132 citations
A phase II randomized trial of RAdium-223 dichloride and SABR versus SABR for oligomEtastatic prostate caNcerS (RAVENS).
Journal of Clinical Oncology2020-05-201 citations
Outcomes of Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer
JAMA Oncology2020-03-261068 citations
AB003. Stereotactic body radiation therapy vs. pulmonary resection
Shanghai Chest2019-09-01
Comparing stereotactic ablative radiotherapy (SABR) versus re-trans-catheter arterial chemoembolization (re-TACE) for hepatocellular carcinoma patients who had incomplete response after initial TACE (TASABR): a randomized controlled trial.
2019-03-2815 citations
A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial).
2018-08-205 citations