Standard of care therapy

DRUG15 trials

Sponsors

Oxford BioMedica, Uta Lichter-Konecki, MiMedx Group, Inc., GlaxoSmithKline, Novartis Pharmaceuticals

Conditions

Advanced Solid TumorCOVID-19Cardiac AL AmyloidosisClear Cell Renal CarcinomaComplicated Urinary Tract InfectionsCoronavirus Disease (COVID-19)Cutaneous T Cell LymphomaEpicondylitis, Lateral Humeral

Phase 1

Radiotherapy With Durvalumab Prior to Surgical Resection for HPV Negative Squamous Cell Carcinoma

CompletedNCT03635164

University of Colorado, DenverSquamous Cell Carcinoma of the Head and Neck

Start: 2018-11-12End: 2023-05-02Updated: 2025-06-27

An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors

RecruitingNCT06589596

BeOne MedicinesAdvanced Solid Tumor

Start: 2024-10-11End: 2029-01-01Target: 244Updated: 2026-03-19

Phase 2

Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants

CompletedNCT01624311

Uta Lichter-KoneckiOrganic Acidemias, Urea Cycle Disorders

Start: 2007-08-31End: 2015-05-31Updated: 2015-06-01

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

TerminatedNCT03345407

GlaxoSmithKlinePulmonary Disease, Chronic Obstructive

Start: 2017-11-28End: 2019-01-10Updated: 2021-07-14

LYS228 PK, Clinical Response, Safety and Tolerability in Patients With Complicated Intra-abdominal Infection (cIAI)

TerminatedNCT03354754

Novartis PharmaceuticalsIntra-abdominal Infections

Start: 2018-05-15End: 2018-09-24Updated: 2021-10-11

LYS228 PK, Clinical Response, Safety and Tolerability in Patients With Complicated Urinary Tract Infection (cUTI)

WithdrawnNCT03377426

Novartis PharmaceuticalsComplicated Urinary Tract Infections

Start: 2018-10-19End: 2019-10-28Updated: 2018-10-26

A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy

TerminatedNCT03474458

Fondazione IRCCS Policlinico San Matteo di PaviaCardiac AL Amyloidosis

Start: 2019-02-11End: 2022-05-30Updated: 2024-07-11

Pembrolizumab Combined With Cisplatin-based Chemotherapy as First-line Systemic Therapy in Advanced Penile Cancer

CompletedNCT04224740

Latin American Cooperative Oncology GroupPenile Carcinoma

Start: 2020-06-15End: 2023-11-13Updated: 2024-03-13

Phase 3

TroVax Renal Immunotherapy Survival Trial

CompletedNCT00397345

Oxford BioMedicaClear Cell Renal Carcinoma

Start: 2006-09-30End: 2009-12-31Updated: 2020-10-19

Pressure injuRy preventiOn by inTermittent EleCtrical sTimulation

TerminatedNCT04328246

AHS Cancer Control AlbertaPressure Injury

Start: 2021-02-26End: 2022-03-14Updated: 2023-01-11

Efficacy and Safety of Favipiravir in Management of COVID-19

CompletedNCT04349241

Ain Shams UniversityCoronavirus Disease (COVID-19)

Start: 2020-04-18End: 2020-06-20Updated: 2020-06-25

Unknown Phase

Micronized Dehydrated Human Amniotic Membrane Suspension in the Treatment of Lateral Epicondylitis

TerminatedNCT01921569

MiMedx Group, Inc.Epicondylitis, Lateral Humeral

Start: 2013-06-30End: 2014-03-31Updated: 2015-09-24

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

RecruitingNCT04045470

Dana-Farber Cancer InstituteCutaneous T Cell Lymphoma, Peripheral T Cell Lymphoma

Start: 2019-12-11End: 2027-01-01Target: 20Updated: 2024-10-08

Impact of More Frequent PT Services

CompletedNCT04778475

Medical University of South CarolinaMobility Limitation, Physical Disability, Stroke, Acute

Start: 2021-06-30End: 2022-10-14Updated: 2023-12-18

COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU

CompletedNCT05302947

Pirogov Russian National Research Medical UniversityCOVID-19, Mild to Moderate

Start: 2020-02-01End: 2021-06-30Updated: 2022-04-08

Related Papers

Pembrolizumab Plus Platinum-Based Chemotherapy for Patients With Advanced Penile Cancer: The Nonrandomized HERCULES (LACOG 0218) Clinical Trial.

2025-11-012 citations

Abstract CT193: Trial in progress: A first-in-human phase 1a/b study of BGB-58067, an MTA-cooperative PRMT5 inhibitor, in patients with advanced solid tumors and MTAP deficiency

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Frequent Error Augmentation Training in Physical Therapy Post Stroke.

2024-06-21

A phase II trial of pembrolizumab plus platinum-based chemotherapy as first-line systemic therapy in advanced penile cancer: HERCULES (LACOG 0218) trial.

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A phase II trial of pembrolizumab combined with platinum-based chemotherapy as first-line systemic therapy in advanced penile cancer: HERCULES (LACOG 0218) trial.

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A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC

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Systemic amyloidosis in a patient presenting with myopathy, peripheral oedema and proteinuria

The Medical Journal of Australia2022-08-04

Safety and efficacy of favipiravir versus hydroxychloroquine in management of COVID-19: A randomised controlled trial.

2021-03-3135 citations

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing <i>In Vitro</i> Susceptibility in Escherichia coli and Klebsiella pneumoniae.

2018-09-2427 citations