Standard of Care (Investigator Selected)

DRUG4 trials

Sponsors

Tongji Hospital, Shanghai Zhongshan Hospital, Stephanie Di Stasi, World Vision US

Conditions

Colorectal NeoplasmsModerate Acute Malnutrition (MAM)OrthopedicPCNSLPrimary Central Nervous System LymphomaTrauma BluntUndernutritionWasting

Phase 2

A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL

RecruitingNCT07350850

Tongji HospitalPCNSL, Primary Central Nervous System Lymphoma

Start: 2025-12-25End: 2029-06-30Target: 77Updated: 2026-06-02

SBRT Followed by PD-1 Inhibitor, Bevacizumab and TAS-102 as Third-Line Therapy for Recurrent/Metastatic Colorectal Cancer

Not yet recruitingNCT07535632

Shanghai Zhongshan HospitalColorectal Neoplasms

Start: 2026-06-01End: 2028-06-01Target: 58Updated: 2026-04-17

Unknown Phase

The Healing and Empowerment Actions for Recovery From Trauma (HEART) Trial

Not yet recruitingNCT07584252

Stephanie Di StasiOrthopedic, Trauma Blunt

Start: 2026-07-01End: 2032-03-01Target: 804Updated: 2026-05-13

Effectiveness of Positive Deviance/Hearth in Treating Uncomplicated Moderate Acute Malnutrition in Children 6-59 Months in Mymensingh Division, Bangladesh

Not yet recruitingNCT07591064

World Vision USModerate Acute Malnutrition (MAM), Undernutrition, Wasting

Start: 2026-05-16End: 2026-12-17Target: 400Updated: 2026-05-15