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SRS

RADIATION8 trials

Sponsors

Lyra Medical Ltd., The George Institute for Global Health, China, Betta Pharmaceuticals Co., Ltd., Juergen Debus, Oncology Institute of Southern Switzerland

Conditions

Anterior Vaginal Wall ProlapseBrain MetastasesBrain Metastases From Solid TumorsBrain Metastases, AdultCancer BrainCardiovascular DiseaseGlioblastomaNon-small Cell Lung Cancer

Phase 2

High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases
NCT02726568
Betta Pharmaceuticals Co., Ltd.Brain Metastases, Non-small Cell Lung Cancer
Start: 2016-03-31End: 2022-12-31Target: 30Updated: 2019-02-19
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma
Active, not recruitingNCT04225039
University of PennsylvaniaGlioblastoma
Start: 2020-06-23End: 2029-04-30Updated: 2025-08-15
SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases
Not yet recruitingNCT07505979
National Taiwan University HospitalBrain Metastases From Solid Tumors
Start: 2026-04-01End: 2031-04-01Target: 90Updated: 2026-04-01

Unknown Phase

Demonstrate the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
CompletedNCT02209337
Lyra Medical Ltd.Anterior Vaginal Wall Prolapse, Vaginal Apex/Uterine Prolapse
Start: 2014-09-30End: 2018-03-31Updated: 2019-08-16
China Rural Health Initiative Follow up Study
CompletedNCT02368418
The George Institute for Global Health, ChinaCardiovascular Disease
Start: 2014-09-30End: 2016-08-31Target: 9164Updated: 2017-02-27
Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases
CompletedNCT03297788
Juergen DebusBrain Metastases, SCLC
Start: 2017-12-01End: 2023-12-01Updated: 2024-01-05
Hypofractionated Brain Radiationcavity
CompletedNCT03561896
Oncology Institute of Southern SwitzerlandBrain Metastases, Adult, Cancer Brain
Start: 2015-01-31End: 2024-06-18Updated: 2024-07-17
The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases?
RecruitingNCT05378633
University Hospital HeidelbergBrain Metastases, Nsclc
Start: 2022-02-24End: 2028-02-24Target: 190Updated: 2026-03-10

Related Papers

PD1 inhibition and GITR agonism in combination with fractionated stereotactic radiotherapy for the treatment of recurrent glioblastoma: A phase 2, multi-arm study.
Journal of Clinical Oncology2023-06-017 citations
A Dutch phase III randomized multicenter trial: whole brain radiotherapy versus stereotactic radiotherapy for 4–10 brain metastases
Neuro-Oncology Advances2021-01-0136 citations
Whole brain radiation therapy alone versus radiosurgery for patients with 1–10 brain metastases from small cell lung cancer (ENCEPHALON Trial): study protocol for a randomized controlled trial
Trials2018-07-1632 citations