SRN-101

DRUG2 trials

Sponsors

Nicholas Butowski, Siren Biotechnology

Conditions

AstrocytomaBrain NeoplasmDiffuse Hemispheric GliomaGlioblastoma (GBM)GliomaOligodendrogliomaRecurrent High Grade GliomasRecurrent High-Grade Gliomas

Phase 1

A Study of SRN-101 Administered Prior to Surgical Resection in Adults With Recurrent High-Grade Glioma.

Not yet recruitingNCT07826949

Nicholas ButowskiRecurrent High-Grade Gliomas, Brain Neoplasm, Glioma

Start: 2026-11-15End: 2032-01-31Target: 6Updated: 2026-10-27

A Study of SRN-101 Gene Therapy in Adults With Recurrent High-Grade Glioma (ALERT-1)

Not yet recruitingNCT07902037

Siren BiotechnologyRecurrent High Grade Gliomas, Glioblastoma (GBM), Astrocytoma +2

Start: 2026-12-01End: 2030-01-01Target: 40Updated: 2026-10-28