SOX

DRUG13 trials

Sponsors

Seoul National University Hospital, Chinese Academy of Medical Sciences, LanZhou University, The First People's Hospital of Changzhou, Peking University

Conditions

Adjuvant TherapyAdvanced Hepatocellular CarcinomaCancer of the StomachChemoradiotherapyChemotherapyColorectal NeoplasmDigestive System DiseasesDigestive System Neoplasms

Phase 1

A Study Evaluating Bemarituzumab in Combination With Other Anti-cancer Therapies in Subjects With Previously Untreated Advanced Gastric or Gastroesophageal Junction Cancer.

Active, not recruitingNCT05322577

AmgenGastric Cancer, Gastroesophageal Junction Cancer

Start: 2022-05-17End: 2026-08-12Updated: 2025-12-05

Phase 2

Trial of Palliative Chemotherapy With TS-1 and Oxaliplatin for Patients With Advanced Hepatocellular Carcinoma

Seoul National University HospitalAdvanced Hepatocellular Carcinoma

Start: 2011-05-31End: 2013-12-31Target: 38Updated: 2011-09-07

A Randomized Phase II Trial of Neoadjuvant Chemotherapy Compared With Chemoradiotherapy in Gastric Adenocarcinoma

CompletedNCT02301481

Chinese Academy of Medical SciencesChemoradiotherapy, Chemotherapy, Neoadjuvant Therapy +1

Start: 2014-01-31End: 2017-12-31Updated: 2019-10-16

A Efficacy and Tolerability Study of TEGAFOX Sequential S-1 in the Treatment of Adjuvant Chemotherapy for Gastric Cancer

LanZhou UniversityGastric Cancer

Start: 2013-05-31End: 2019-05-31Target: 300Updated: 2016-06-29

SOX Versus XELOX for Patients With Peritoneal Metastasis of Colorectal Cancer

The First People's Hospital of ChangzhouColorectal Neoplasm

Start: 2013-01-31End: 2019-06-30Target: 60Updated: 2016-08-19

Study to Evaluate the Efficiency of SOX as Seconde-line Chemotherapy in Neuroendocrine Carcinoma

Peking UniversityNeuroendocrine Carcinoma

Start: 2017-09-01End: 2020-09-01Target: 45Updated: 2017-09-12

An Investigational Study of Immunotherapy Combinations With Chemotherapy in Patients With Gastric or Gastroesophageal Junction (GEJ) Cancers

CompletedNCT03662659

Bristol-Myers SquibbCancer of the Stomach, Esophagogastric Junction, Gastric Cancer

Start: 2018-10-16End: 2024-01-18Updated: 2025-02-05

A Phase II Study of Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer

Jing Jin, M.D.Gastric Cancer, Neoadjuvant Therapy

Start: 2019-11-20End: 2023-09-21Target: 82Updated: 2022-01-24

PD-1 Antibody Adjuvant Therapy for GC Patients With MSI-H After D2 Radical Surgery

Fudan UniversityAdjuvant Therapy, Gastric Cancer, MSI-H +1

Start: 2022-08-25End: 2025-12-31Target: 141Updated: 2022-08-26

Efficacy and Safety of SOX Regimen Combined With Camrelizumab as Neoadjuvant Treatment in Locally Advanced Gastric Cancer: a Phase II, Single-arm Study

Active, not recruitingNCT05602935

The Second Affiliated Hospital of Fujian Medical UniversityDigestive System Diseases, Digestive System Neoplasms, Neoplasms +3

Start: 2020-09-16End: 2026-12-30Target: 29Updated: 2023-09-28

AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer

RecruitingNCT06196697

Harbin Medical UniversityGastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma

Start: 2024-04-10End: 2027-03-31Target: 50Updated: 2024-06-27

A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis

RecruitingNCT06685887

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyGastric Cancer

Start: 2025-02-15End: 2027-12-31Target: 34Updated: 2025-04-11

Unknown Phase

A Prospective Cohort Study on the Treatment of Locally Advanced Gastric Cancer

RecruitingNCT06760858

Southwest Hospital, ChinaGastric Cancer, Gastroesophageal Junction Cancer

Start: 2024-12-01End: 2029-09-01Target: 122Updated: 2025-01-07

Related Papers

Cadonilimab in combination with ivonescimab and chemotherapy as first-line (1L) therapy in patients with advanced gastric (G) or gastroesophageal junction adenocarcinoma (GEJA).

Journal of Clinical Oncology2025-05-28

A prospective phase II clinical trial of total neoadjuvant therapy for locally advanced gastric cancer and gastroesophageal junction adenocarcinoma.

2024-03-294 citations

Total neoadjuvant therapy for locally advanced gastric cancer and esophagogastric junction adenocarcinoma: study protocol for a prospective, multicenter, single-arm, phase II clinical trial.

2022-07-288 citations

Preoperative Concurrent Chemoradiotherapy Versus Neoadjuvant Chemotherapy for Locally Advanced Gastric Cancer: Phase II Randomized Study

Frontiers in Oncology2022-04-299 citations

Preoperative versus postoperative chemo-radiotherapy for locally advanced gastric cancer: a multicenter propensity score-matched analysis

BMC Cancer2022-02-268 citations

Total Neoadjuvant Therapy for Locally Advanced Gastric Cancer: An Interim Study of Phase Ⅱ Clinical Trial.

2021-11-01

CA224-060: A randomized, open label, phase II trial of relatlimab (anti-LAG-3) and nivolumab with chemotherapy versus nivolumab with chemotherapy as first-line treatment in patients with gastric or gastroesophageal junction adenocarcinoma.

Journal of Clinical Oncology2019-05-2023 citations

A phase II trial of S-1 and oxaliplatin in patients with advanced hepatocellular carcinoma

BMC Cancer2018-03-058 citations