Sotevtamab

BIOLOGICAL2 trials

Sponsors

Alethia Biotherapeutics, ImmunityBio, Inc.

Conditions

Metastatic Colorectal CancerPancreatic CancerPancreatic Cancer Resectable

Phase 1

Open-Label, Phase 1 Clinical Trial of Neoadjuvant Nogapendekin Alfa Inbakicept, Sotevtamab, and Zabadinostat in Combination With Gemcitabine and Nab-Paclitaxel for Participants With Borderline Resectable or Locally Advanced Pancreatic Cancer

Not yet recruitingNCT07488884

ImmunityBio, Inc.Pancreatic Cancer, Pancreatic Cancer Resectable

Start: 2026-03-01End: 2029-06-01Target: 30Updated: 2026-03-23

Phase 2

Sotevtamab (AB-16B5) Combined With FOLFOX as Neoadjuvant Treatment Prior to Resection of Colorectal Cancer Liver Metastasis

RecruitingNCT06225843

Alethia BiotherapeuticsMetastatic Colorectal Cancer

Start: 2024-02-15End: 2026-06-30Target: 17Updated: 2025-02-19