Sotagliflozin (SAR439954)
Sponsors
Lexicon Pharmaceuticals, Sanofi
Conditions
Diabetes MellitusHealthy SubjectsType 1 Diabetes MellitusType 2 Diabetes Mellitus
Phase 1
A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol
CompletedNCT02940379
Start: 2016-10-31End: 2016-12-31Updated: 2022-04-25
Effect of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin
CompletedNCT03063580
Start: 2017-02-27End: 2017-05-12Updated: 2022-04-25
Interaction Study to Evaluate the Effects of Mefenamic Acid on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin in Healthy Male and Female Subjects
CompletedNCT03070678
Start: 2017-03-14End: 2017-04-18Updated: 2022-04-25
A Study to Evaluate the Effect of Food on the Pharmacokinetics of Sotagliflozin and to Explore the Relative Bioavailability in Healthy Subjects
CompletedNCT03174548
Start: 2017-06-12End: 2017-09-15Updated: 2022-04-25
Sotagliflozin Bioequivalence Study
CompletedNCT03211195
Start: 2017-06-29End: 2017-08-22Updated: 2022-04-25
Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects
CompletedNCT03310944
Start: 2017-10-18End: 2017-12-08Updated: 2022-04-13
A Drug to Drug Interaction Study of Sotagliflozin With Hydrochlorothiazide
CompletedNCT03387657
Start: 2018-01-03End: 2018-03-02Updated: 2022-04-25
A Drug-Drug Interaction Study Between Sotagliflozin and Ramipril
CompletedNCT03414723
Start: 2018-01-15End: 2018-03-10Updated: 2022-04-25
A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions
CompletedNCT03776227
Start: 2019-01-25End: 2019-04-22Updated: 2022-04-25
Study To Determine Bioavailability of Sotagliflozin in Healthy Male and Female Subjects
CompletedNCT03802487
Start: 2019-01-14End: 2019-03-28Updated: 2022-04-25
Sotagliflozin Multiple-dose Study in Healthy Chinese Subjects
CompletedNCT03909451
Start: 2019-04-28End: 2019-08-19Updated: 2022-04-25
Phase 2
Phase 3
Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin
CompletedNCT02926950
Start: 2016-11-30End: 2019-03-22Updated: 2021-05-11
Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic Therapy
CompletedNCT02926937
Start: 2016-11-11End: 2019-05-17Updated: 2021-06-21
Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With Metformin
CompletedNCT03066830
Start: 2017-02-24End: 2019-04-30Updated: 2021-05-11
Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy
CompletedNCT03332771
Start: 2017-12-01End: 2019-09-06Updated: 2021-05-11
Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea
TerminatedNCT03761134
Start: 2018-11-30End: 2020-04-29Updated: 2022-04-25
Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Diet and Exercise
TerminatedNCT03760965
Start: 2018-11-27End: 2020-04-24Updated: 2022-04-25