sorfequiline

DRUG2 trials

Sponsors

Global Alliance for TB Drug Development

Conditions

Drug Sensitive TuberculosisPulmonary TBPulmonary TuberculosisTuberculosis, Pulmonary

Phase 2

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, With Pretomanid and Linezolid in Adults With Drug-sensitive Pulmonary Tuberculosis

Active, not recruitingNCT06058299

Global Alliance for TB Drug DevelopmentDrug Sensitive Tuberculosis, Pulmonary TB, Pulmonary Tuberculosis

Start: 2023-10-31End: 2027-02-01Updated: 2026-06-24

Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TB

RecruitingNCT07672405

Global Alliance for TB Drug DevelopmentTuberculosis, Pulmonary

Start: 2026-07-09End: 2028-06-24Target: 100Updated: 2026-07-15

Related Papers

Cardiodynamic evaluation of sorfequiline (TBAJ-876): results from a first-in-human study

Antimicrobial Agents and Chemotherapy2026-01-30

Protocol for a phase 2, partially blinded, randomized trial assessing the safety and efficacy of sorfequiline or bedaquiline in combination with pretomanid and linezolid in adult participants with newly diagnosed, drug-sensitive, smear-positive pulmonary tuberculosis (NC-009).

2026-01-06

Contribution of telacebec to novel drug regimens in a murine tuberculosis model

Antimicrobial Agents and Chemotherapy2024-12-094 citations