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DRUG3 trials

Sponsors

Hospices Civils De Lyon, Hopital NOVO, Centre Hospitalier Universitaire De Montpellier

Conditions

Obese children and adolescentsThyroidectomy is a common operation. Transient postoperative hypocalcemia is the main complicationTransient hypercalciurialonger hospital stays and increased perioperative cost. Cholecalciferol is used to supplement vitamin D deficiency. We suppose that systematic pre-operative supplementation with cholecalciferol would allow a faster and more appropriate response to post-operative hypocalcemiaresulting in clinical discomfort for patients

Phase 3

OBEVIDOS “Treatment of vitamin D deficit in obese children and adolescents: an open label randomized controlled study comparing the efficacy of two oral supplementation regimens: monthly boluses versus daily doses for correcting blood vitamin D level.”
RecruitingCTIS2023-507089-18-00
Hospices Civils De LyonObese children and adolescents
Start: 2023-11-24Target: 68Updated: 2025-11-05
Study of post-total thyroidectomy hypocalcemia after preoperative cholecalciferol supplementation.
Not yet recruitingCTIS2024-516793-30-00
Hopital NOVOlonger hospital stays and increased perioperative cost. Cholecalciferol is used to supplement vitamin D deficiency. We suppose that systematic pre-operative supplementation with cholecalciferol would allow a faster and more appropriate response to post-operative hypocalcemia, resulting in clinical discomfort for patients, Thyroidectomy is a common operation. Transient postoperative hypocalcemia is the main complication
Target: 200Updated: 2025-07-25

Phase 4

DonneDVit : Assessing the Impact of a Mode of Vitamin D Supplementation (Sequential Dose vs Daily Dose) on the Incidence of Hypercalciuria in Subjets Aged From 2 to 18 Years. Randomized controlled trial with 2 parallel groups.
Not yet recruitingCTIS2024-518219-20-00
Centre Hospitalier Universitaire De MontpellierTransient hypercalciuria
Target: 280Updated: 2025-02-28