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Solu-Cortef

DRUG5 trials

Sponsors

Amsterdam UMC Stichting, Copenhagen University Hospital, Haukeland University Hospital, Beni-Suef University

Conditions

Addison DiseaseAdrenal Hyperplasia CongenitalOral Pyogenic GranulomaPancreatic conditions requiring pancreaticoduodenectomySevere acute infectionType 1 Diabetessuch as pancreatic head carcinoma or intraductal papillary mucinous neoplasms (IPMN).

Phase 1

Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia
CompletedNCT02096510
Haukeland University HospitalAddison Disease, Adrenal Hyperplasia Congenital
Start: 2014-03-27End: 2017-12-31Updated: 2024-06-07

Phase 2

Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes
TerminatedNCT01840189
Haukeland University HospitalAddison Disease, Type 1 Diabetes
Start: 2013-04-24End: 2016-12-31Updated: 2024-03-01
Corticosteroid Intralesional Injection as an Alternative Treatment in Oral Pyogenic Granuloma in the Esthetic Zone.
NCT05534334
Beni-Suef UniversityOral Pyogenic Granuloma
Start: 2022-05-01End: 2022-11-29Target: 30Updated: 2022-09-14

Phase 4

Preventing postoperative complications in patients undergoing high-risk pancreatoduodenectomy with a bundle approach including hydrocortisone, ocreotide, and teres ligament patch (PANENCA): an international randomized controlled multicenter trial
RecruitingCTIS2024-519667-18-00
Amsterdam UMC StichtingPancreatic conditions requiring pancreaticoduodenectomy, such as pancreatic head carcinoma or intraductal papillary mucinous neoplasms (IPMN).
Start: 2025-08-21Target: 400Updated: 2025-10-29
Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections (IMPACT)
WithdrawnCTIS2025-522215-42-00
Copenhagen University HospitalSevere acute infection
Target: 300Updated: 2025-12-08