sofosbuvir/velpatasvir

DRUG12 trials

Sponsors

Kirby Institute, Ala'a Sharara, Elizabeth Krans, MD, Brigham and Women's Hospital, Mary E. Keebler, MD

Conditions

A key focus of the study is hepatitis C, but HIV and hepatitis B are also included. The target population includes people who currently use or inject drugs, those with a history of drug use or injection, and their sexual or life partners. People Who Inject Drugs Hepatitis C HIV, Hepatitis BAwaiting Organ TransplantCardiac TransplantHeart TransplantHepatitis CHepatitis C, ChronicKidney TransplantationLiver Transplant

Phase 2

Expanding the Pool in Orthotopic Heart Transplantation

Active, not recruitingNCT03222531

Mary E. Keebler, MDCardiac Transplant, Heart Transplant, Hepatitis C

Start: 2017-08-01End: 2026-05-31Target: 20Updated: 2025-12-09

The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients

Active, not recruitingNCT03809533

Amit D Tevar, MDHepatitis C, Kidney Transplantation

Start: 2019-05-29End: 2026-04-01Updated: 2025-11-06

The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients

CompletedNCT03819322

Fernanda P Silveira, MD, MSHepatitis C, Liver Transplant

Start: 2019-08-15End: 2025-03-17Updated: 2025-08-12

Phase 4

Surveillance and Treatment of Prisoners With Hepatitis C

CompletedNCT02064049

Kirby InstituteHepatitis C

Start: 2014-10-31End: 2019-11-30Updated: 2019-12-09

Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial

CompletedNCT03032666

Ala'a ShararaHepatitis C, Thalassemia

Start: 2017-05-01End: 2018-08-06Updated: 2018-10-11

Sofosbuvir/Velpatasvir in Postpartum Women With Opioid Use Disorder and Chronic Hepatitis C Infection

CompletedNCT03057847

Elizabeth Krans, MDHepatitis C, Chronic, Opioid-use Disorder

Start: 2018-01-30End: 2022-02-24Updated: 2023-05-06

Transplanting Hepatitis C Positive Organs

Brigham and Women's HospitalAwaiting Organ Transplant, Hepatitis C

Start: 2017-03-01End: 2023-12-31Target: 148Updated: 2022-10-12

A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic

CompletedNCT03235154

Community Research Initiative of New EnglandHepatitis C, Hepatitis C, Chronic, Opiate Dependence

Start: 2017-10-11End: 2019-09-26Updated: 2021-05-13

Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant

CompletedNCT03619837

University of California, San FranciscoHepatitis C, Transplantation Disease Transmission

Start: 2018-07-15End: 2020-08-13Updated: 2021-03-03

Unknown Phase

Test and Treat HIV and Viral Hepatitis for People Who Use Drugs and Their Partners in Thailand

Active, not recruitingTCTR20171115002

Dreamlopments FoundationA key focus of the study is hepatitis C, but HIV and hepatitis B are also included. The target population includes people who currently use or inject drugs, those with a history of drug use or injection, and their sexual or life partners. People Who Inject Drugs Hepatitis C HIV, Hepatitis B

Start: 2019-05-27Target: 3000Updated: 2026-03-30

A TEst and Treat Intervention aMong Current People Who Inject Drugs With HCV Attending Needle and Syringe PrOgrams

CompletedNCT03492112

Kirby InstituteHepatitis C

Start: 2019-09-10End: 2021-11-30Updated: 2023-01-17

Hepatitis C Treatment in Idaho County Jails

Not yet recruitingNCT06533319

Eastern Idaho Public HealthHepatitis C

Start: 2024-08-01End: 2025-08-01Target: 100Updated: 2024-08-01

Related Papers

Scale-up of Direct-Acting Antiviral Treatment in Prisons Is Both Cost-effective and Key to Hepatitis C Virus Elimination

Open Forum Infectious Diseases2023-12-189 citations

Hepatitis C Virus Reinfection Following Direct-Acting Antiviral Treatment in the Prison Setting: The SToP-C Study

Clinical Infectious Diseases2022-03-2927 citations

Evaluation of hepatitis C treatment-as-prevention within Australian prisons (SToP-C): a prospective cohort study.

2021-05-0768 citations

87. Heart and Lung Transplants From HCV-Viremic Donors to Uninfected Patients: Longer-Term Follow-Up

Open Forum Infectious Diseases2019-10-012 citations

Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients

New England Journal of Medicine2019-04-03318 citations