Sodium Thiosulfate (STS)

DRUG4 trials

Sponsors

Sidney Kimmel Cancer Center at Thomas Jefferson University, TRPHARM, Robyn T. Domsic, MD, MPH, Yale University

Conditions

CalcinosisCalcinosis CutisCancerCisplatin-Induced Hearing Loss in Children Who Had Standard-risk HepatoblastomaDermatomyositisMixed Connective Tissue Disease (MCTD)Systemic Sclerosis (SSc)

Phase 2

Intralesional Injection of STS in Treatment of Calcinosis

RecruitingNCT06672822

Robyn T. Domsic, MD, MPHCalcinosis, Dermatomyositis, Mixed Connective Tissue Disease (MCTD) +1

Start: 2025-03-17End: 2029-05-01Target: 20Updated: 2026-05-05

Unknown Phase

The Effect of Sodium Thiosulfate Eardrops on Hearing Loss in Patients Who Receive Cisplatin Therapy

TerminatedNCT01369641

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityCancer

Start: 2011-08-24End: 2013-05-02Updated: 2025-05-16

A Compassionate Use Program to Provide Access to Sodium Thiosulfate

TRPHARMCisplatin-Induced Hearing Loss in Children Who Had Standard-risk Hepatoblastoma

Updated: 2021-09-16

Quantification of Calcinosis Cutis Disease Burden Using Computed Tomography Images

RecruitingNCT07228429

Yale UniversityCalcinosis Cutis, Systemic Sclerosis (SSc)

Start: 2025-10-14End: 2026-07-01Target: 56Updated: 2026-02-17