sodium stibogluconate

DRUG12 trials

Sponsors

Drugs for Neglected Diseases, The Cleveland Clinic, Case Comprehensive Cancer Center, M.D. Anderson Cancer Center, Waisenmedizin e. V. Promoting Access to Essential Medicine

Conditions

Acute Myeloid LeukemiaAdvanced CancerCancerCutaneous LeishmaniasisMyelodysplastic SyndromesMyeloid MalignancyP53 MutationPrimary Visceral Leishmaniasis

Phase 1

Sodium Stibogluconate and Interferon in Treating Patients With Advanced Solid Tumors, Lymphoma, or Myeloma

TerminatedNCT00311558

The Cleveland ClinicCancer

Start: 2005-10-31End: 2012-01-31Updated: 2018-01-26

Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers

CompletedNCT00498979

Case Comprehensive Cancer CenterStage IV Melanoma

Start: 2007-05-31End: 2012-01-31Updated: 2020-07-24

Sodium Stibogluconate With Interferon Alpha-2b for Patients With Advanced Malignancies

CompletedNCT00629200

M.D. Anderson Cancer CenterAdvanced Cancer, Solid Tumors

Start: 2006-09-13End: 2010-02-10Updated: 2018-11-15

Phase I/II Trial of Sodium Stibogluconate in Myelodysplastic Syndrome

TerminatedNCT01009502

Northwestern UniversityMyelodysplastic Syndromes

Start: 2009-07-31End: 2013-05-31Updated: 2013-11-08

Phase 2

Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients

CompletedNCT00996463

Waisenmedizin e. V. Promoting Access to Essential MedicineWound Healing

Start: 2010-01-31End: 2011-03-31Target: 63Updated: 2011-03-28

A Study of the Efficacy and Safety of the LEISH-F2 + MPL-SE Vaccine for Treatment of Cutaneous Leishmaniasis

CompletedNCT01011309

Access to Advanced Health Institute (AAHI)Cutaneous Leishmaniasis

Start: 2009-10-31End: 2011-12-31Updated: 2013-12-11

Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations

First Affiliated Hospital of Jinan UniversityAcute Myeloid Leukemia, Myelodysplastic Syndromes, Myeloid Malignancy +3

Start: 2020-06-01End: 2024-02-01Target: 5Updated: 2021-06-09

African leishmaniasis: From clinical research to access

Active, not recruitingPACTR202205775486864

Armauer Hansen Research InstituteUncomplicated Cutaneous Leishmaniasis Skin and Connective Tissue Diseases

Start: 2022-06-30Target: 326Updated: 2026-01-27

LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study

CompletedNCT05957978

Drugs for Neglected DiseasesPrimary Visceral Leishmaniasis

Start: 2024-03-29End: 2025-11-13Updated: 2025-12-18

Phase 3

Efficacy/Safety of Sodium Stibogluconate (SSG) Versus Paromomycin (PM) and SSG/PM Combination to Treat V Leishmaniasis

CompletedNCT00255567

Drugs for Neglected DiseasesVisceral Leishmaniasis

Start: 2004-11-30End: 2010-01-31Updated: 2016-03-22

Miltefosine/Paromomycin Phase III Trial for Treatment of Primary Visceral Leishmaniasis (VL) Patients in Eastern Africa

CompletedNCT03129646

Drugs for Neglected DiseasesVisceral Leishmaniasis

Start: 2018-01-24End: 2020-12-11Updated: 2024-02-29

Phase 4

Efficacy of Radio-frequency Induced Heat (RFH)Therapy in Treatment of Cutaneous Leishmaniasis in India

CompletedNCT01661296

Sarder Patel Medical CollegeCutaneous Leishmaniasis

Start: 2009-08-31End: 2011-12-31Updated: 2012-09-03

Related Papers

Efficacy and safety of 14-day treatment with paromomycin and miltefosine for primary visceral leishmaniasis in eastern Africa: non-inferiority trial

2023-01-01

Paromomycin and Miltefosine Combination as an Alternative to Treat Patients With Visceral Leishmaniasis in Eastern Africa: A Randomized, Controlled, Multicountry Trial

Clinical Infectious Diseases2022-09-2764 citations

A randomized controlled phase IIb wound healing trial of cutaneous leishmaniasis ulcers with 0.045% pharmaceutical chlorite (DAC N-055) with and without bipolar high frequency electro-cauterization versus intralesional antimony in Afghanistan

BMC Infectious Diseases2014-11-2421 citations

Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial.

2012-06-19112 citations