Sodium Chloride 0.9% Intravenous Infusion BP
Sponsors
Lassen Therapeutics 1 Inc., Prinses Maxima Centrum voor Kinderoncologie B.V., Astellas Pharma Global Development Inc., Imperial College London Limited
Conditions
Claudin (CLDN)18.2-PositiveHER2-NegativeHIVLocally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) AdenocarcinomaMetastatic Gastric or Gastroesophageal Junction (GEJ) AdenocarcinomaNeuroblastomaThyroid Eye Disease
Phase 1
Phase 2
A Phase 2, Proof-of-Concept, Randomized, Double-Masked, Placebo-Controlled Study to Determine the Efficacy and Safety of LASN01 in Patients with Thyroid Eye Disease
CompletedCTIS2023-508161-32-00
Start: 2024-03-28End: 2025-04-02Target: 11Updated: 2025-04-11
The RIO Trial: A randomised placebo controlled trial of ART plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) vs ART plus placebo in treated Primary or Early stage HIV Infection on viral control off ART
RecruitingCTIS2024-514564-13-00
Start: 2025-01-02Target: 21Updated: 2025-11-21
Phase 3
A Phase 3, Global, Multi-Center, Double-Blind, Randomized, Efficacy Study of Zolbetuximab (IMAB362) Plus mFOLFOX6 Compared with Placebo Plus mFOLFOX6 as First-line Treatment of Subjects with Claudin (CLDN)18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Active, not recruitingCTIS2024-511365-11-00
Start: 2018-11-27Target: 210Updated: 2026-01-15
A Phase 3, Global, Multi-Center, Double-Blind, Randomized, Efficacy Study of Zolbetuximab (IMAB362) Plus CAPOX Compared with Placebo Plus CAPOX as First-line Treatment of Subjects with Claudin (CLDN) 18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
Active, not recruitingCTIS2024-511648-16-00
Start: 2019-01-04Target: 108Updated: 2025-10-03