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Sodium Benzoate

DRUG6 trials

Sponsors

Klinikum der Technischen Universitaet Muenchen (TUM Klinikum), National Center for Research Resources (NCRR), Niuvanniemi Hospital, Baylor College of Medicine, Pakistan Institute of Living and Learning

Conditions

Amino Acid Metabolism, Inborn ErrorsAttenuated or Transient PsychosisChronic Liver DiseaseCorticobasal Syndrome (CBS)Schizoaffective DisorderSchizophreniaSchizophreniform DisordersUrea Cycle Disorders, Inborn

Phase 2

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders
CompletedNCT00004767
National Center for Research Resources (NCRR)Amino Acid Metabolism, Inborn Errors
Start: 1985-01-31Target: 20Updated: 2005-06-24
Sodium Benzoate for Treatment of Attenuated/Transient Psychosis. A Randomized Placebo-controlled Trial.
WithdrawnNCT02026947
Niuvanniemi HospitalAttenuated or Transient Psychosis
Start: 2014-02-28End: 2016-12-31Updated: 2014-04-10
Sodium Benzoate and/or N-Acetylcysteine Added to TAU in Patients With Early Schizophrenia Spectrum Disorder.
CompletedNCT03510741
Pakistan Institute of Living and LearningSchizoaffective Disorder, Schizophrenia, Schizophreniform Disorders
Start: 2019-01-01End: 2021-03-30Updated: 2022-04-27
Double-blind, randomised, prospective, placebo controlled parallel group phase II study to investigate the effect of glycerol phenylbutyrate (GPB) on neurofilament light chain (NfL) levels in patients with corticobasal syndrome (CBS)
Active, not recruitingCTIS2024-516897-31-00
Klinikum der Technischen Universitaet Muenchen (TUM Klinikum)Corticobasal Syndrome (CBS)
Start: 2023-12-01Target: 32Updated: 2025-09-18

Unknown Phase

Comparative Efficacy of Phenylbutyrate (PBA) vs. Benzoate in Urea Cycle Disorders
CompletedNCT02111200
Baylor College of MedicineUrea Cycle Disorders, Inborn
Start: 2014-09-30End: 2015-10-31Updated: 2018-01-09
Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.
CompletedNCT04022941
Institute of Liver and Biliary Sciences, IndiaChronic Liver Disease
Start: 2017-04-01End: 2018-12-31Updated: 2019-07-17

Related Papers

Study protocol: double-blind, randomized, prospective, placebo controlled parallel group phase II study to investigate the effect of glycerol phenylbutyrate (GPB) on neurofilament light chain (NfL) levels in patients with corticobasal syndrome (CBS)
Neurological Research and Practice2026-07-03
Add-on Sodium Benzoate and <i>N</i>-Acetylcysteine in Patients With Early Schizophrenia Spectrum Disorder: A Multicenter, Double-Blind, Randomized Placebo-Controlled Feasibility Trial
Schizophrenia Bulletin Open2024-01-013 citations