SMOFlipid

DRUG15 trials

Conditions

CholestasisCovid19Crohn DiseaseDietary and Nutritional TherapiesEnd-stage Liver DiseaseGrowth FailureHome Parenteral NutritionIntestinal Fistula

Phase 1

SMOFlipid to Lessen the Severity of Neonatal Cholestasis

TerminatedNCT02721277

University of FloridaCholestasis, Jaundice, Obstructive

Start: 2016-05-31End: 2017-02-02Updated: 2017-04-17

LIPIDS-P Trial Phase I/II Trial

CompletedNCT03405870

University of FloridaSepsis, Severe, Septic Shock

Start: 2018-08-17End: 2023-04-26Updated: 2025-08-11

Phase 3

A Fatty Acids Study in Preventing Retinopathy of Prematurity

CompletedNCT02760472

Carola Pfeiffer-MosessonRetinopathy of Prematurity

Start: 2013-03-31End: 2015-09-30Updated: 2016-05-03

Lipid Emulsion Infusion and COVID-19 Patients

CompletedNCT04957940

Assiut UniversityCovid19

Start: 2021-07-05End: 2021-09-26Updated: 2021-09-28

Phase 4

Preventing Cholestasis Using SMOFLipid®

CompletedNCT01585935

Medical University of ViennaCholestasis, Psychomotor Disorders, Developmental

Start: 2012-06-30End: 2017-11-13Updated: 2018-01-09

Pilot Study: Hepatoprotective Role of SMOFlipid® Used in Short-term Parenteral Nutrition in an Onco-Hematology Pediatric Population

CompletedNCT02539316

Centre Hospitalier Universitaire de NiceDietary and Nutritional Therapies

Start: 2015-06-30End: 2016-10-31Updated: 2017-04-13

Reduction of Neonatal Parenteral Nutrition Associated Cholestasis Through Lipid Emulsions

TerminatedNCT02633384

Centro Hospitalar de Lisboa CentralIntrahepatic, Cholestasis

Start: 2011-08-31End: 2017-04-30Updated: 2017-07-13

SMOFLipid in Patients Who Are Intralipid Intolerant

WithdrawnNCT03054948

Mayo ClinicHome Parenteral Nutrition, Short Bowel Syndrome

Start: 2017-02-01End: 2018-03-20Updated: 2018-03-22

Safety and Efficacy Study to Compare Smoflipid and Intralipid 20% in Pediatric Patients of 3 Months to 16 Years of Age

TerminatedNCT03563222

Fresenius KabiMalnutrition, Child

Start: 2019-12-18End: 2022-07-08Updated: 2022-12-12

Effects of Fat Emulsions on PNALD and Oxidative Stress in Premature Infants

NCT04277923

Shanghai Jiao Tong University School of MedicinePreterm Infant

Start: 2020-02-29End: 2021-08-31Target: 66Updated: 2020-02-20

Unknown Phase

Omega 3 Lipid Emulsions and Liver Transplantation

NCT01957943

Mansoura UniversityIschemia Re-perfusion Injury

Start: 2014-05-31End: 2018-03-31Target: 114Updated: 2017-03-28

SMOF Lipid for Children With Parenteral Nutrition Induced Liver Injury

NCT02412566

Baylor College of MedicineCholestasis, Growth Failure

Updated: 2025-08-19

Intralipid Versus SMOFlipid in HPN Patients

CompletedNCT03773237

Mayo ClinicCrohn Disease, Intestinal Fistula, Intestinal Obstruction +1

Start: 2018-12-31End: 2024-10-01Updated: 2025-05-16

Supplements SMOF in TPN for Liver Transplantation Recipients

CompletedNCT04572373

Chang Gung Memorial HospitalEnd-stage Liver Disease, Liver Transplantation, Total Parenteral Nutrition

Start: 2012-01-01End: 2015-06-30Updated: 2020-10-08

Lipid Emulsion in Cardiac Valve Replacement Surgery

NCT04951791

Assiut UniversityIschemic Reperfusion Injury

Start: 2021-08-31End: 2023-10-31Target: 68Updated: 2021-07-07

The Journal of Pediatrics2022-10-176 citations

Could early infusion of fish-oil-based lipid emulsion affect the need for intensive care in moderately diseased COVID-19 patients? A randomized clinical trial

Ain-Shams Journal of Anaesthesiology2022-07-161 citations

Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants.

2022-06-0913 citations

Lipid intensive drug therapy for sepsis pilot: A Bayesian phase I clinical trial.

2020-11-189 citations

IGF1, serum glucose, and retinopathy of prematurity in extremely preterm infants

JCI Insight2020-10-0134 citations

Serum choline in extremely preterm infants declines with increasing parenteral nutrition.

2020-06-259 citations

A Randomized Trial of Parenteral Nutrition Using a Mixed Lipid Emulsion Containing Fish Oil in Infants of Extremely Low Birth Weight: Neurodevelopmental Outcome at 12 and 24 Months Corrected Age, A Secondary Outcome Analysis.

2020-06-2315 citations

LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock

BMJ Open2019-09-0122 citations

A Mixed Lipid Emulsion Containing Fish Oil and Its Effect on Electrophysiological Brain Maturation in Infants of Extremely Low Birth Weight: A Secondary Analysis of a Randomized Clinical Trial.

2019-04-259 citations

Association of Retinopathy of Prematurity With Low Levels of Arachidonic Acid

JAMA Ophthalmology2018-02-0875 citations

A Mixed Lipid Emulsion for Prevention of Parenteral Nutrition Associated Cholestasis in Extremely Low Birth Weight Infants: A Randomized Clinical Trial.

2017-12-1855 citations

Parenteral nutrition-associated cholestasis and triglyceridemia in surgical term and near-term neonates: A pilot randomized controlled trial of two mixed intravenous lipid emulsions.

2017-08-2619 citations