SIRT

PROCEDURE9 trials

Sponsors

Fox Chase Cancer Center, Johannes Gutenberg University Mainz, Charite University, Berlin, Germany, Jiping Wang, MD, PhD, Sirtex Medical

Conditions

Hepatocellular CancerHepatocellular CarcinomaHepatocellular Carcinoma Non-ResectableIntrahepatic Cholangiocellular CarcinomaLiver Metastases From Colorectal Cancer (mCRC)Metastatic Liver CancerResectable Hepatocellular CarcinomaUnresectable Hepatocellular Carcinoma

Phase 1

Study of Capecitabine in Combination With SIR-Spheres in Patients With Advanced Cancer

CompletedNCT00604409

Fox Chase Cancer CenterMetastatic Liver Cancer

Start: 2006-04-30End: 2015-01-31Updated: 2015-09-07

SIRT With Tremelimumab and Durvalumab for Resectable HCC

RecruitingNCT05701488

Jiping Wang, MD, PhDHepatocellular Cancer, Hepatocellular Carcinoma, Resectable Hepatocellular Carcinoma

Start: 2023-04-21End: 2026-10-01Target: 20Updated: 2025-09-02

Phase 2

Selective Internal Radiotherapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Cholangiocellular Carcinoma (CCC).

Johannes Gutenberg University MainzIntrahepatic Cholangiocellular Carcinoma

Start: 2011-02-28End: 2018-06-30Target: 24Updated: 2017-05-23

Transarterial Radioembolisation in Comparison to Transarterial Chemoembolisation in Uveal Melanoma Liver Metastasis

CompletedNCT02936388

Charite University, Berlin, GermanyUveal Melanoma

Start: 2016-01-31End: 2024-12-31Updated: 2025-01-24

Y-90 SIRT for Unresectable HCC Larger Than 7cm

RecruitingNCT06707233

Second Affiliated Hospital of Guangzhou Medical UniversityHepatocellular Carcinoma Non-Resectable

Start: 2024-12-01End: 2027-11-30Target: 33Updated: 2025-01-28

Phase 4

Selective Internal Radiation Therapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Hepatocellular Carcinoma (HCC).

CompletedNCT01798160

Johannes Gutenberg University MainzHepatocellular Carcinoma

Start: 2010-02-28End: 2013-05-31Target: 24Updated: 2015-10-20

Unknown Phase

Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)

RecruitingNCT05967143

Sirtex MedicalLiver Metastases From Colorectal Cancer (mCRC), Unresectable Hepatocellular Carcinoma (HCC)

Start: 2023-06-19End: 2029-06-30Target: 845Updated: 2024-11-27

SIRT for Potentially Resectable HCC

RecruitingNCT05994859

Second Affiliated Hospital of Guangzhou Medical UniversityHepatocellular Carcinoma

Start: 2023-08-10End: 2027-02-09Target: 35Updated: 2023-09-14

SIRT Versus cTACE for Unresectable HCC (CHANCE2506)

RecruitingNCT06909708

Zhongda HospitalUnresectable Hepatocellular Carcinoma

Start: 2025-04-03End: 2027-01-30Target: 108Updated: 2025-04-09

Related Papers

First interim analysis of the SirTac trial: A randomized phase II study of SIRT and DSM-TACE in patients with liver metastases from uveal melanoma.

Journal of Clinical Oncology2022-06-018 citations

Selective internal radiotherapy (SIRT) versus transarterial chemoembolization (TACE) for the treatment of intrahepatic cholangiocellular carcinoma (CCC): study protocol for a randomized controlled trial.

2014-08-0619 citations