SIR-Sphere

DEVICE3 trials

Sponsors

St. Joseph's Hospital, Florida, Assistance Publique - Hôpitaux de Paris, University of California, San Francisco

Conditions

Breast Cancer Metastatic to the LiverColon CancerLiver CarcinomaLiver MetastasesRectal Cancer

Phase 1

Tas-102 and Radioembolization With 90Y Resin Microspheres for Chemo-refractory Colorectal Liver Metastases

CompletedNCT02602327

University of California, San FranciscoColon Cancer, Liver Metastases, Rectal Cancer

Start: 2017-01-09End: 2021-08-31Updated: 2022-08-01

Phase 2

Brachytherapy Radiation Directly to the Liver in Breast Cancer Patients With Metastatic to Liver

TerminatedNCT00891800

St. Joseph's Hospital, FloridaBreast Cancer Metastatic to the Liver

Start: 2007-07-31End: 2010-12-31Target: 50Updated: 2011-06-07

Phase 3

SorAfenib Versus RADIOEMBOLIZATION in Advanced Hepatocellular Carcinoma

CompletedNCT01482442

Assistance Publique - Hôpitaux de ParisLiver Carcinoma

Start: 2011-12-31End: 2016-04-30Updated: 2017-01-16

Related Papers

Phase I prospective trial of TAS-102 (trifluridine and tipiracil) and radioembolization with <sup>90</sup>Y resin microspheres for chemo-refractory colorectal liver metastases.

2022-12-1311 citations

Cost-Utility Analysis of Transarterial Radioembolization With Yttrium-90 Resin Microspheres Compared With Sorafenib in Locally Advanced and Inoperable Hepatocellular Carcinoma.

2021-05-284 citations

Relationship of Tumor Radiation–absorbed Dose to Survival and Response in Hepatocellular Carcinoma Treated with Transarterial Radioembolization with <sup>90</sup>Y in the SARAH Study

Radiology2020-06-30185 citations

Phase I prospective trial of TAS-102 (trifluride and tipiracil) and radioembolization with 90Y resin microspheres for chemo-refractory colorectal liver metastases.

Journal of Clinical Oncology2020-02-012 citations

Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial.

2017-10-26553 citations

VESPRO: An Individual Patient Data Prospective Meta-Analysis of Selective Internal Radiation Therapy Versus Sorafenib for Advanced, Locally Advanced, or Recurrent Hepatocellular Carcinoma of the SARAH and SIRveNIB Trials

JMIR Research Protocols2017-02-1511 citations

Radioembolisation with yttrium‒90 microspheres versus sorafenib for treatment of advanced hepatocellular carcinoma (SARAH): study protocol for a randomised controlled trial.

2014-12-0336 citations

Multicenter Phase II Study of Sequential Radioembolization-Sorafenib Therapy for Inoperable Hepatocellular Carcinoma

PLoS ONE2014-03-1067 citations