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Sintilimab plus Chemotherapy

DRUG5 trials

Sponsors

Fudan University, Sun Yat-sen University, The First Hospital of Jilin University, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, First Affiliated Hospital of Ningbo University

Conditions

Esophageal Squamous Cell CarcinomaEsophagogastric Junction AdenocarcinomaGastric AdenocarcinomaLocalized Advanced Rectal AdenocarcinomaLung CancerSoft Tissue Sarcoma

Phase 2

Sintilimab Plus Chemotherapy Followed by dCRT in Locally Advanced ESCC
CompletedNCT03985046
Fudan UniversityEsophageal Squamous Cell Carcinoma
Start: 2019-10-10End: 2022-12-31Updated: 2024-11-07
Adriamycin and Ifosfamide Combined With Sintilimab
RecruitingNCT04589754
Sun Yat-sen UniversitySoft Tissue Sarcoma
Start: 2021-07-26End: 2026-07-30Target: 176Updated: 2024-01-02
Sintilimab Combined With Chemotherapy as Adjuvant Treatment for Phase III GC and GEJ
RecruitingNCT06761846
Cancer Institute and Hospital, Chinese Academy of Medical SciencesEsophagogastric Junction Adenocarcinoma, Gastric Adenocarcinoma
Start: 2025-01-17End: 2028-12-31Target: 70Updated: 2026-04-21

Phase 4

Intestinal Microbiota Transplantation, Radiochemotherapy and Sintilimab in Localized Advanced Colon Cancer
Enrolling by invitationNCT06931808
First Affiliated Hospital of Ningbo UniversityLocalized Advanced Rectal Adenocarcinoma
Start: 2025-03-01End: 2028-08-01Target: 20Updated: 2025-04-17

Unknown Phase

Detection of Minimal Residual Disease in Resectable Stage II-IIIB Non-small Cell Lung Cancer
NCT06267144
The First Hospital of Jilin UniversityLung Cancer
Start: 2024-01-20End: 2025-12-17Target: 20Updated: 2024-02-20

Related Papers

Induction sintilimab and chemotherapy followed by concurrent chemoradiotherapy for locally advanced esophageal cancer: a proof-of-concept, single-arm, multicenter, phase 2 trial.
2024-02-0628 citations