Single Agent Therapy

DRUG4 trials

Sponsors

Mayo Clinic, City of Hope Medical Center, Theodore Brasky PhD

Conditions

GliomaHematopoietic and Lymphatic System NeoplasmInsomniaMalignant Solid NeoplasmRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia

Early Phase 1

Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease

RecruitingNCT07025226

Mayo ClinicGlioma

Start: 2025-08-12End: 2027-09-01Target: 30Updated: 2026-07-02

Phase 1

BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation

Not yet recruitingNCT07583303

City of Hope Medical CenterRecurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia

Start: 2026-12-14End: 2027-04-16Target: 19Updated: 2026-05-13

Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial

Not yet recruitingNCT07658677

Theodore Brasky PhDHematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm

Start: 2026-09-01End: 2027-12-31Target: 50Updated: 2026-06-22

Phase 2

THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia

Not yet recruitingNCT07565974

Mayo ClinicInsomnia, Malignant Solid Neoplasm

Start: 2026-06-01End: 2027-09-01Target: 69Updated: 2026-05-04