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Simvastatin 20mg

DRUG7 trials

Sponsors

University of Sao Paulo, University of Oxford, Jinnah Sindh Medical University, National Cancer Institute, Naples, Post Graduate Institute of Medical Education and Research, Chandigarh

Conditions

Acute Kidney InjuryAdenocarcinoma of the PancreasAdvanced Biliary Tract CarcinomaCirrhosis, LiverCirrhotic CardiomyopathyCoronary Heart DiseaseDecompensated CirrhosisDepression

Early Phase 1

Protective Effect of Zingiber Officinale L. Extract in Hypertensive Patients
CompletedNCT05682911
Jinnah Sindh Medical UniversityThe Main Focus of This Study is to Evaluate the Safety of Zingiber Officinale L. Tablets as Hypolipidemic Agent in Hypertensive Patients
Start: 2018-01-01End: 2018-06-30Updated: 2023-01-12

Phase 1

7-day Simvastatin and Emotional Processing
CompletedNCT04652089
University of OxfordDepression, Inflammation
Start: 2020-12-03End: 2021-09-01Updated: 2022-11-03
Adebrelimab Combined With Gemcitabine, Cisplatin, and Simvastatin for Advanced Biliary Tract Cancer
RecruitingNCT07392541
Tongji HospitalAdvanced Biliary Tract Carcinoma
Start: 2026-01-30End: 2028-01-30Target: 29Updated: 2026-03-23

Phase 2

Valproic Acid/Simvastatin Plus Gemcitabine/Nab-paclitaxel Based Regimens in Untreated Metastatic Pancreatic Adenocarcinoma Patients
RecruitingNCT05821556
National Cancer Institute, NaplesAdenocarcinoma of the Pancreas
Start: 2023-06-12End: 2026-06-30Target: 240Updated: 2025-07-29

Phase 4

Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons
CompletedNCT00481351
University of Sao PauloCoronary Heart Disease
Start: 2007-06-30End: 2010-01-31Updated: 2011-01-26

Unknown Phase

Simvastatin and Emotional Processing (OxSTEP)
CompletedNCT04973800
University of OxfordDepression, Inflammation
Start: 2021-07-05End: 2023-02-16Updated: 2024-06-26
Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival
RecruitingNCT06431919
Post Graduate Institute of Medical Education and Research, ChandigarhAcute Kidney Injury, Cirrhosis, Liver, Cirrhotic Cardiomyopathy +2
Start: 2025-06-10End: 2028-02-29Target: 260Updated: 2025-06-08

Related Papers

Randomized phase 2 study of valproic acid combined with simvastatin and gemcitabine/nab-paclitaxel-based regimens in untreated metastatic pancreatic adenocarcinoma patients: the VESPA trial study protocol.
2024-09-195 citations
An experimental medicine study of the effects of simvastatin on emotional processing, reward learning, verbal memory, and inflammation in healthy volunteers.
2022-05-058 citations