Silibinin

DRUG6 trials

Conditions

Amanita PoisoningAmatoxin PoisoningBrain Metastases, AdultBreast CancerHCV Recurrence After Liver TransplantationHepatitis CLiver FailureMushroom Poisoning

Phase 1

Trial of Indole-3-Carbinol and Silibinin

CompletedNCT03687073

Masonic Cancer Center, University of MinnesotaSmoking

Start: 2018-11-29End: 2021-05-07Updated: 2021-08-11

Phase 2

Intravenous Silibinin in Combination With Peg-interferon and Ribavirin in Nonresponders

CompletedNCT00684268

Medical University of ViennaHepatitis C

Start: 2007-10-31End: 2011-06-30Updated: 2017-03-27

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

TerminatedNCT00915681

Mylan Specialty, LPAmanita Poisoning, Amatoxin Poisoning, Liver Failure +1

Start: 2009-11-10End: 2020-04-10Updated: 2022-04-07

Legalon SIL for the Treatment of HCV Recurrence in Liver Transplanted Patients

TerminatedNCT01535092

RottapharmHCV Recurrence After Liver Transplantation

Start: 2010-09-30End: 2011-11-30Updated: 2012-02-17

Unknown Phase

SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)

RecruitingNCT05689619

A.O.U. Città della Salute e della ScienzaBrain Metastases, Adult, Breast Cancer, Non Small Cell Lung Cancer

Start: 2023-09-01End: 2027-09-01Target: 70Updated: 2023-12-15

Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin

Active, not recruitingNCT05793489

Istituto Clinico HumanitasBrain Metastases, Adult

Start: 2023-03-06End: 2026-03-30Target: 44Updated: 2025-04-24

Related Papers

Elimination drives recovery in amatoxin-induced acute liver failure A globally applicable management framework: preserving toxin elimination enables transplant-free recovery

2026-03-05

TMIC-07. pSTAT3 expression in patients with brain metastases from breast cancer: association with molecular subtypes and impact on overall survival

Neuro-Oncology2025-11-01

P11.06.A PATTERNS OF PSTAT3 EXPRESSION IN REACTIVE ASTROCYTES OF BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER AND CORRELATIONS WITH OUTCOME

Neuro-Oncology2025-10-01

TMIC-08. PATTERNS OF PSTAT3 EXPRESSION IN REACTIVE ASTROCYTES OF BRAIN METASTASES FROM NON-SMALL CELL LUNG CANCER AND CORRELATIONS WITH OUTCOME

Neuro-Oncology2024-11-01

P17.22.B SILMET TRIAL: A RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE STAT3 INHIBITOR SILIBININ IN PREVENTING INTRACRANIAL RECURRENCE AFTER COMPLETE RESECTION OF A SINGLE BRAIN METASTASIS FROM NON-SMALL-CELL LUNG CANCER (NSCLC) OR BREAST CANCER

Neuro-Oncology2024-10-01

RTID-02. SILMET TRIAL: A RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE SILIBININ IN PREVENTING INTRACRANIAL RECURRENCE AFTER COMPLETE RESECTION OF A SINGLE BRAIN METASTASIS FROM NSCLC OR BREAST CANCER

Neuro-Oncology2023-11-01