SHR-8068

DRUG11 trials

Conditions

Advanced Hepatocellular CarcinomaAdvanced Solid TumorsBiliary Tract CancerColorectal CancerGastric AdenocarcinomaGastroesophageal AdenocarcinomaHER2-positive Locally Advanced or Metastatic Biliary Tract CancerImmunotherapy

Phase 1

Study of SHR-8068 Combined With Adebrelimab and Bevacizumab in the Treatment of Advanced Hepatocellular Carcinoma

RecruitingNCT05444088

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Advanced Hepatocellular Carcinoma

Start: 2022-08-02End: 2026-06-30Target: 129Updated: 2024-06-21

SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer

Not yet recruitingNCT06373133

West China HospitalColorectal Cancer

Start: 2024-05-01End: 2026-11-01Target: 36Updated: 2024-04-18

A Study of SHR-A2102 in Combination With Adebrelimab and SHR-8068 in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

RecruitingNCT06589778

Shanghai Hengrui Pharmaceutical Co., Ltd.Non-Small Cell Lung Cancer

Start: 2024-09-27End: 2026-04-30Target: 124Updated: 2024-11-12

A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With Solid Tumors

RecruitingNCT06703177

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Advanced Solid Tumors

Start: 2025-02-18End: 2027-07-01Target: 876Updated: 2025-12-03

A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC

RecruitingNCT06754930

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Non-small Cell Lung Cancer (NSCLC)

Start: 2025-02-18End: 2027-12-31Target: 400Updated: 2025-04-17

SHR-A1811 Combination Regimen for the Treatment of Recurrent or Metastatic Cervical Cancer

RecruitingNCT06859775

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Recurrent or Metastatic Cervical Cancer

Start: 2025-04-25End: 2027-01-31Target: 100Updated: 2025-06-06

Phase 2

Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer

RecruitingNCT06465563

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Biliary Tract Cancer

Start: 2024-07-01End: 2026-12-30Target: 80Updated: 2025-01-27

A Clinical Study of SHR-A1811 in the Treatment of HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer

RecruitingNCT06778031

Suzhou Suncadia Biopharmaceuticals Co., Ltd.HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer

Start: 2025-02-26End: 2028-09-30Target: 54Updated: 2025-03-06

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma：A Randomized, Non-comparative Phase 2 Study

Not yet recruitingNCT07266025

Shanghai Zhongshan HospitalGastric Adenocarcinoma, Gastroesophageal Adenocarcinoma, Immunotherapy +1

Start: 2026-01-30End: 2030-06-30Target: 30Updated: 2026-01-27

Umbrella Trial of Neoadjuvant Therapy for Locally Advanced Colorectal Cancer

Not yet recruitingNCT07503639

Fudan UniversityLocally Advanced Colorectal Cancer

Start: 2026-04-01End: 2030-04-01Target: 134Updated: 2026-03-31

Phase 3

Study of SHR-8068 Combined With Adebrelimab and Bevacizumab Versus Sintilimab Combined With Bevacizumab for the Treatment of Advanced Hepatocellular Carcinoma

RecruitingNCT06618664

Suzhou Suncadia Biopharmaceuticals Co., Ltd.Advanced Hepatocellular Carcinoma

Start: 2024-10-28End: 2030-12-31Target: 590Updated: 2025-05-15

Related Papers

SHR-8068 plus adebrelimab and bevacizumab for advanced hepatocellular carcinoma (aHCC): A phase 1b/2 study.