Short-course Radiation

RADIATION3 trials

Sponsors

Jong Hoon Lee, Sir Run Run Shaw Hospital

Conditions

MSS Locally Advanced Rectal AdenocarcinomaRectal AdenocarcinomaRectal Cancer

Phase 2

Short-course Preoperative Chemoradiotherapy for Rectal Cancer

Jong Hoon LeeRectal Cancer

Start: 2011-09-30End: 2017-10-31Target: 80Updated: 2017-10-10

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM)

CompletedNCT05216653

Sir Run Run Shaw HospitalMSS Locally Advanced Rectal Adenocarcinoma

Start: 2022-04-07End: 2025-03-05Updated: 2025-03-13

The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma

RecruitingNCT06266832

Sir Run Run Shaw HospitalRectal Adenocarcinoma

Start: 2024-01-01End: 2027-12-31Target: 30Updated: 2024-02-20

Related Papers

Phase II study of neoadjuvant short-course radiotherapy combined with CAPEOX plus envafolimab in patients with microsatellite stable locally advanced rectal cancer: Updated results of PRECAM study.

Journal of Clinical Oncology2024-06-011 citations

Efficacy and safety of neoadjuvant preoperative short-course radiation followed by envafolimab plus CAPEOX in microsatellite stable (MSS)/mismatch repair proficient (pMMR) locally advanced rectal cancer.

Journal of Clinical Oncology2023-01-247 citations

One-week versus two-week chemoradiotherapy followed by curative surgery in rectal cancer: Long-term comparative pooled analysis of two prospective multicenter phase II trials.

Journal of Clinical Oncology2023-01-241 citations

The Impact of Surgical Timing on Pathologic Tumor Response after Short Course and Long Course Preoperative Chemoradiation for Locally Advanced Rectal Adenocarcinoma.

2017-11-218 citations

Two-week course of preoperative chemoradiotherapy followed by delayed surgery for rectal cancer: a phase II multi-institutional clinical trial (KROG 11-02).

2014-01-0720 citations