Shingrix powder and suspension for suspension for injection Herpes zoster vaccine (recombinant
Sponsors
Universitair Medisch Centrum Groningen, Universitair Medisch Centrum Groningen, Centre Hospitalier Universitaire De Bordeaux, GlaxoSmithKline Biologicals, Merck Healthcare KGaA, Justus-Liebig-Universitaet Giessen
Conditions
COVID-19Generalized Myasthenia GravisHerpes ZosterHerpes Zoster virus preventionHuman Immunodeficiency Virus (HIV)Incident dementiaPsoriasis vulgaris and/or psoriatric arthritisimpaired immunity
Phase 2
Phase 3
Prospective Randomized trial of Everolimus replacing MMF/MP Acid by the RECOVAC consortium to increase VACcine response in kidney transplant patients
CompletedCTIS2023-503894-39-00
Start: 2023-08-22End: 2024-02-27Target: 110Updated: 2023-10-10
A phase 3b, open-label, multi-country, multi-centre, long-term follow-up study of ZOSTER-049 (follow- up of ZOSTER-006/022 studies) to assess the prophylactic efficacy, safety and persistence of immune response of a Herpes Zoster subunit vaccine and assessment of persistence of immune response and safety of 1 or 2 additional doses administered in ZOSTER-049 in 2 subgroups of older adults.
Active, not recruitingCTIS2023-505255-51-00
Start: 2022-08-08Target: 2157Updated: 2025-09-23
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 3-Arm, 3-Period Study to Assess the Efficacy and Safety of a New Formulation of Oral Cladribine Compared with Placebo in Participants with Generalized Myasthenia Gravis (MyClad)
RecruitingCTIS2023-507746-83-00
Start: 2024-11-27Target: 69Updated: 2025-11-26
Phase 4
Safety and immunogenicity of Shingrix vaccination in patients suffering from Psoriasis or Psoriatic arthritis
RecruitingCTIS2024-512881-32-00
Start: 2023-11-22Target: 336Updated: 2025-12-02
Characterization of the immune response in immunosuppressed patients with rheumatic diseases, including to the recombinant zoster vaccine
Not yet recruitingCTIS2024-518190-34-00
Target: 60Updated: 2025-09-04
Herpes zoster after recombinant herpes zoster vaccination - Immediate post-RHZ-vaccination evolution of CMI, HMI and lymphocyte count and typing.
Not yet recruitingCTIS2025-521547-20-00
Target: 10Updated: 2026-01-05
A randomized, placebo controlled, observer-blind, phase IV pragmatic trial to evaluate the effect of Recombinant Zoster Vaccine (Shingrix®) on incident dementia diagnosis in an older adult population aged ≥76 years in Finland
Not yet recruitingCTIS2025-524598-17-00
Target: 35000Updated: 2026-02-16
A Pragmatic Randomized Trial to Evaluate the Effect of Recombinant Herpes Zoster Vaccine on Major Adverse Cardiovascular Events and Dementia in Adults Aged 65 Years or Above
Not yet recruitingCTIS2025-524944-37-00
Target: 162000Updated: 2026-03-04