Sham surgery

PROCEDURE13 trials

Sponsors

Sangamo Therapeutics, SanBio, Inc., Astellas Institute for Regenerative Medicine, Living Cell Technologies, University of Denver

Conditions

Age-Related Macular DegenerationAllergic RhinitisChronic Ischemic StrokeChronic RhinitisEustachian Tube DysfunctionIdiopathic Parkinson's DiseaseLymphedema ArmLymphedema of Leg

Phase 1

Safety and Efficacy of CERE-120 in Subjects With Parkinson's Disease

CompletedNCT00985517

Sangamo TherapeuticsIdiopathic Parkinson's Disease

Start: 2009-10-29End: 2017-11-16Updated: 2020-04-16

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

CompletedNCT05603312

MeiraGTx, LLCParkinson's Disease

Start: 2022-10-05End: 2024-09-06Updated: 2025-09-05

Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies

RecruitingNCT06683365

Craig van Horne, MD, PhDMultiple System Atrophy, Parkinsons Disease

Start: 2025-02-25End: 2030-12-02Target: 7Updated: 2026-04-01

A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke

Not yet recruitingNCT07318714

Astellas Pharma IncChronic Ischemic Stroke

Start: 2026-04-07End: 2030-02-28Target: 84Updated: 2026-04-03

Phase 2

Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson's Disease

CompletedNCT00400634

Sangamo TherapeuticsIdiopathic Parkinson's Disease

Start: 2006-11-30End: 2008-11-30Updated: 2022-11-10

Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke

CompletedNCT02448641

SanBio, Inc.Chronic Ischemic Stroke

Start: 2016-03-08End: 2018-12-05Updated: 2020-10-08

Study to Evaluate Sub-retinal Transplantation of Retinal Pigmented Epithelial Cells in Patients With Dry AMD

WithdrawnNCT02563782

Astellas Institute for Regenerative MedicineAge-Related Macular Degeneration

Start: 2015-08-24End: 2017-05-05Updated: 2017-07-26

Investigation of the Safety and Efficacy of NTCELL® [Immunoprotected (Alginate-Encapsulated) Porcine Choroid Plexus Cells for Xenotransplantation] in Patients With Parkinson's Disease

CompletedNCT02683629

Living Cell TechnologiesParkinson's Disease

Start: 2016-02-29End: 2019-05-02Updated: 2019-05-14

Phase 3

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

RecruitingNCT06944522

BlueRock TherapeuticsParkinsons Disease (PD)

Start: 2025-06-17End: 2032-03-01Target: 102Updated: 2026-04-01

Unknown Phase

Double-blind Placebo Surgery Trial for Treatment of Parkinson's Disease

CompletedNCT03347955

University of DenverParkinson Disease, Surgery

Start: 1994-11-30End: 1999-02-28Updated: 2017-11-20

Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis.

RecruitingNCT04645511

Tampere University HospitalEustachian Tube Dysfunction, Maxillary Sinusitis, Sinusitis, Chronic +1

Start: 2021-06-01End: 2027-12-31Target: 120Updated: 2022-10-20

The N-LVA Study: RCT Comparing LVA vs. Sham Surgery in Cancer-related Lymphedema

RecruitingNCT06082349

Maastricht University Medical CenterLymphedema Arm, Lymphedema, Lower Limb, Lymphedema of Leg +2

Start: 2023-12-18End: 2029-03-01Target: 110Updated: 2026-01-16

Laser Posterior Nasal Nerve Neurolysis

Active, not recruitingNCT07050992

Chiayi Christian HospitalAllergic Rhinitis, Chronic Rhinitis, Nasal Allergies +5

Start: 2024-11-01End: 2026-12-31Target: 120Updated: 2025-12-17

Related Papers

The N-LVA Study: effectiveness and cost-effectiveness of lymphaticovenous anastomosis (LVA) for patients with cancer who suffer from chronic peripheral lymphoedema – study protocol of a multicentre, randomised sham-controlled trial

BMJ Open2024-04-012 citations

Parkinson's disease gene therapy: a comparative effectiveness review of completed clinical trials in terms of their possible implementation in treatment

MEDICAL SCIENCE PULSE2023-02-271 citations

Neurotrophic factors: promising candidates in tissue regeneration

Neural Regeneration Research2016-01-0113 citations

Gene delivery of AAV2-neurturin for Parkinson's disease: a double-blind, randomised, controlled trial.

2010-10-20469 citations