SGLT-2 inhibitor

DRUG11 trials

Conditions

DiabetesDuchenne Muscular Dystrophy (DMD)Erectile DysfunctionHeart FailureHeart Failure Due to Coronary Artery DiseaseHeart Failure With Preserved Ejection Fraction (HFPEF)Heart Failure With Reduced Ejection FractionKidney Transplantation Recipients

Phase 1

Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors

RecruitingNCT06753994

McGill UniversityDiabetes, T1D, Type1diabetes

Start: 2024-12-05End: 2027-01-01Target: 24Updated: 2024-12-31

Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy

Not yet recruitingNCT07172971

Larry W. MarkhamDuchenne Muscular Dystrophy (DMD)

Start: 2026-02-01End: 2028-02-01Target: 10Updated: 2025-12-24

Phase 4

SGLT2i and Incretin and CRTd.

CompletedNCT03282136

University of Campania Luigi VanvitelliHeart Failure, Type 2 Diabetes Mellitus

Start: 2017-09-01End: 2024-09-01Updated: 2025-06-25

SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency

TerminatedNCT05737186

Peking University People's HospitalHeart Failure With Reduced Ejection Fraction, Renal Insufficiency, Chronic

Start: 2023-03-09End: 2024-04-16Updated: 2024-04-30

SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients

RecruitingNCT07143773

Odense University HospitalKidney Transplantation Recipients, Non-Diabetic Patients, Placebo Control Design +2

Start: 2025-09-01End: 2027-08-01Target: 88Updated: 2025-08-27

Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists

Active, not recruitingNCT07325435

MaryAnn BanerjiType 2 Diabetes (T2DM)

Start: 2024-12-21End: 2028-06-30Target: 60Updated: 2026-01-08

Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome

CompletedNCT07563647

Kafrelsheikh UniversityErectile Dysfunction, Left Ventricular Diastolic Dysfunction, Metabolic Syndrome

Start: 2025-05-05End: 2026-03-17Updated: 2026-05-04

Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot Study

Not yet recruitingNCT07572032

Kyungsub SongHeart Failure, Heart Failure Due to Coronary Artery Disease, Valvular Cardiomyopathy

Start: 2026-05-20End: 2028-12-20Target: 80Updated: 2026-05-07

Unknown Phase

Hydroxyl Free Radical Associated Effects of SGLT-2 Inhibitors in Type 2 Diabetes

CompletedNCT06797115

University of PecsT2DM

Start: 2022-07-18End: 2024-06-30Updated: 2025-01-28

The Use of Advanced Imaging in HFpEF

RecruitingNCT06905405

Sheffield Teaching Hospitals NHS Foundation TrustHeart Failure With Preserved Ejection Fraction (HFPEF)

Start: 2025-08-05End: 2027-09-30Target: 40Updated: 2026-03-18

SGLT2 Inhibitors and Survival in Lung Cancer Patients With Diabetes

Not yet recruitingNCT07272057

Shanghai Chest HospitalLung Cancer

Start: 2025-12-07End: 2026-11-07Target: 200Updated: 2025-12-09

Related Papers

Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor agonists (GLP-1 RA) therapy vs. conventional hypoglycemic drugs: arrhythmic burden, hospitalizations for heart failure, and CRTd responders rate