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Senna

DRUG12 trials

Sponsors

London North West Healthcare NHS Trust, Shirley Ryan AbilityLab, Hong Kong Baptist University, Shiraz University of Medical Sciences, TriHealth Inc.

Conditions

Autistic DisorderBowel ObstructionBowel PreparationChronic Idiopathic ConstipationColostomyConstipationElective SurgeryEncopresis

Early Phase 1

Senna vs. Polyethylene Glycol 3350 for the Treatment of Retentive Encopresis in Children
Not yet recruitingNCT07604025
Shaare Zedek Medical CenterEncopresis With Constipation and Overflow Incontinence
Start: 2026-07-01End: 2028-01-01Target: 80Updated: 2026-06-18

Phase 1

Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
RecruitingNCT04113382
Ferring PharmaceuticalsBowel Preparation
Start: 2022-06-23End: 2027-12-01Target: 39Updated: 2026-09-04

Phase 2

A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation
CompletedNCT01695850
Hong Kong Baptist UniversityFunctional Constipation, Gastrointestinal Disorders
Start: 2013-06-30End: 2015-08-31Updated: 2020-05-12

Phase 3

Bowel Preparation and Prokinetics in Capsule Endoscopy
NCT00275184
London North West Healthcare NHS TrustGastrointestinal Hemorrhage, Refractory Anemia, Small Bowel Disease
Start: 2006-01-31Target: 150Updated: 2007-09-24

Phase 4

PEG3350 vs Senna After Urogyn Surgery
RecruitingNCT06825260
St. Joseph's Health, New YorkObstructive Defecation Syndrome, Postoperative Constipation
Start: 2025-04-23End: 2027-07-31Target: 254Updated: 2025-05-28

Unknown Phase

Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation
CompletedNCT00662363
Shirley Ryan AbilityLabConstipation
Start: 2008-04-30End: 2011-10-31Updated: 2013-03-06
Evaluating the Effect of Senna in Uremic Pruritus
CompletedNCT02008864
Shiraz University of Medical SciencesEnd Stage Renal Disease, Pruritus
Start: 2011-08-31Updated: 2015-04-01
Efficacy of Linaclotide to Senna for CIC
TerminatedNCT02239510
TriHealth Inc.Chronic Idiopathic Constipation
Start: 2014-09-30End: 2016-06-30Updated: 2019-07-02
An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders
CompletedNCT02383758
Emory UniversityAutistic Disorder, Encopresis
Start: 2015-02-01End: 2017-01-01Updated: 2018-07-02
Gut Transit Effect on Enterohepatic Circulation
CompletedNCT03501498
University Hospital Plymouth NHS TrustIntestinal Transit
Start: 2017-04-10End: 2022-03-01Updated: 2022-09-30
Bowel Preparation in Elective Pediatric Colorectal Surgery
NCT03593252
McMaster UniversityBowel Obstruction, Colostomy, Elective Surgery +4
Start: 2022-01-01End: 2024-01-30Target: 81Updated: 2021-12-09
RELISTOR's Effects on Opioid-Induced Constipation
WithdrawnNCT04930237
Methodist Health SystemOIC
Start: 2021-07-01End: 2022-04-22Updated: 2026-03-23

Related Papers

Pre-operative mechanical bowel preparation and prophylactic oral antibiotics for pediatric patients undergoing elective colorectal surgery: a protocol for a randomized controlled feasibility trial.
2024-05-25
Efficacy of MaZiRenWan, a Chinese Herbal Medicine, in Patients With Functional Constipation in a Randomized Controlled Trial.
2018-04-1231 citations
Chinese herbal medicine (Ma Zi Ren Wan) for functional constipation: study protocol for a prospective, double-blinded, double-dummy, randomized controlled trial.
2013-11-0418 citations