Senicapoc

DRUG8 trials

Sponsors

Lillebaelt Hospital, Icagen, University of Aarhus, University of California, Davis, Vejle Hospital

Conditions

ARDS, HumanAlzheimer DiseaseAtopic AsthmaCOVIDExercise Induced AsthmaGlioblastomaIdiopathic Pulmonary FibrosisMild Cognitive Impairment

Early Phase 1

Senicapoc and Perampanel for Newly Diagnosed Glioblastoma

RecruitingNCT07284069

Aarhus University HospitalGlioblastoma

Start: 2026-03-01End: 2028-11-01Target: 36Updated: 2026-05-07

Phase 2

Study to Assess Safety and Efficacy of Oral Senicapoc Administration on Exercise-induced Asthma

CompletedNCT00861185

IcagenExercise Induced Asthma

Start: 2009-03-31End: 2009-09-30Updated: 2011-07-14

Safety and Efficacy Study of Oral Senicapoc on Allergen Challenge in Atopic Asthmatic Subjects

CompletedNCT00861211

IcagenAtopic Asthma

Start: 2008-10-31End: 2009-05-31Updated: 2011-07-14

Senicapoc in COVID-19 Patients With Severe Respiratory Insufficiency

University of AarhusARDS, Human, COVID

Start: 2020-04-24End: 2021-12-31Target: 46Updated: 2020-10-20

Senicapoc in Alzheimer's Disease

RecruitingNCT04804241

University of California, DavisAlzheimer Disease, Mild Cognitive Impairment

Start: 2022-03-18End: 2027-12-01Target: 55Updated: 2026-08-17

Senicapoc in patients with Progressive Fibrotic ILD (Interstitial Lung Disease) or IPF (Idiopathic Pulmonary Fibrosis) to prevent progression.

RecruitingCTIS2024-511131-97-00

Lillebaelt HospitalProgressive Fibrotic Interstitial Lung Disease

Start: 2025-08-10Target: 100Updated: 2024-11-22

Senicapoc in Patients With Worsening Fibrotic Interstitial Lung Disease

RecruitingNCT06714123

Vejle HospitalIdiopathic Pulmonary Fibrosis, Pulmonary Fibrosis, Interstitial Lung Disease

Start: 2025-08-01End: 2028-12-01Target: 140Updated: 2026-05-07

Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

RecruitingNCT07282210

Biossil Inc.Sickle Cell Anaemia, Sickle Cell Anemia, Sickle Cell Disease

Start: 2026-08-13End: 2029-02-01Target: 105Updated: 2026-08-17