Selexipag
Sponsors
Actelion, University of Sao Paulo General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust
Conditions
BioequivalenceCardiodynamicsChronic Thromboembolic Pulmonary HypertensionHealthy SubjectsHypertension, PulmonaryNon-healing WoundPharmacokineticsPulmonary Arterial Hypertension
Phase 1
Study of Selexipag and Its Metabolite ACT-333679 on Cardiac Repolarization in Healthy Male and Female Subjects
CompletedNCT02206204
Start: 2012-06-30End: 2012-11-30Updated: 2014-08-01
Study in Healthy Male Subjects to Demonstrate Bioequivalence of 1600 μg Selexipag Administered as Eight Tablets of 200 μg or as Single Tablet of 1600 μg
CompletedNCT02206295
Start: 2012-09-30End: 2012-12-31Updated: 2025-02-03
A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects
CompletedNCT02770222
Start: 2016-06-30End: 2016-07-31Updated: 2025-02-03
Potential Pharmacokinetic Interaction Between Selexipag and Midazolam in Healthy Male Subjects
CompletedNCT02791815
Start: 2016-07-31End: 2016-09-30Updated: 2016-10-13
A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects
CompletedNCT03496506
Start: 2018-03-05End: 2018-05-18Updated: 2025-06-22
Phase 2
Effects of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis
CompletedNCT02260557
Start: 2014-10-31End: 2015-06-30Updated: 2025-02-03
A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag
TerminatedNCT03942211
Start: 2021-02-26End: 2023-04-19Updated: 2024-05-08
Selexipag for the Treatment of Schistosomiasis-Associated Pulmonary Arterial Hypertension
NCT04589390
Start: 2020-10-15End: 2022-03-31Target: 20Updated: 2020-10-19
Phase 3
Selexipag (ACT-293987) in Pulmonary Arterial Hypertension
CompletedNCT01106014
Start: 2009-12-01End: 2014-10-01Updated: 2025-10-27
Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension
CompletedNCT02471183
Start: 2015-10-12End: 2016-12-05Updated: 2018-01-23
The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension
CompletedNCT02558231
Start: 2016-05-01End: 2020-04-20Updated: 2025-03-30
A Study to Find Out if Selexipag is Effective and Safe in Patients With Chronic Thromboembolic Pulmonary Hypertension When the Disease is Inoperable or Persistent/Recurrent After Surgery and/or Interventional Treatment
TerminatedNCT03689244
Start: 2019-01-23End: 2022-06-07Updated: 2024-06-21
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
Active, not recruitingNCT04175600
Start: 2020-01-16End: 2027-10-01Updated: 2026-03-13
A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study
CompletedNCT04565990
Start: 2021-05-03End: 2023-11-10Updated: 2025-05-01
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
RecruitingNCT05179876
Start: 2022-05-04End: 2028-02-29Target: 280Updated: 2026-03-13
Phase 4
Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.
CompletedNCT03078907
Start: 2017-11-08End: 2020-02-10Updated: 2025-03-30
Pulmonary Hypertension: Intensification and Personalisation of Combination Rx
RecruitingNCT05825417
Start: 2023-06-14End: 2026-01-31Target: 40Updated: 2024-12-03
Unknown Phase
Individual Patient Expanded Access IND for Selexipag (Uptravi) in Participants With Non-healing Wound, Buerger's Disease
NCT04914247
Updated: 2026-03-27
Patient-Reported Outcomes and Adherence After Transition From Inhaled Iloprost to Oral Selexipag in Pulmonary Arterial Hypertension
Not yet recruitingNCT07356375
Start: 2026-03-01End: 2026-12-31Target: 32Updated: 2026-02-13
Related Papers
8 more papers not shown