Selatogrel

COMBINATION_PRODUCT6 trials

Sponsors

Viatris Innovation GmbH

Conditions

Acute Myocardial InfarctionChronic Coronary SyndromeHealthy SubjectsHealthy VolunteersHepatic ImpairmentStable Coronary Artery Disease

Phase 1

The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics

CompletedNCT04406896

Viatris Innovation GmbHHealthy Subjects, Hepatic Impairment

Start: 2020-07-22End: 2020-10-23Updated: 2025-07-04

A Comparative Study of Selatogrel (ACT-246475) Formulations in Healthy Subjects

CompletedNCT04557280

Viatris Innovation GmbHHealthy Subjects

Start: 2020-11-06End: 2020-12-19Updated: 2025-07-03

A Trial to Compare What the Body Does to Selatogrel and the Effect of Selatogrel in Japanese and Caucasian Healthy Participants

CompletedNCT07133191

Viatris Innovation GmbHHealthy Volunteers

Start: 2025-10-07End: 2025-11-06Updated: 2026-07-14

A Trial to Compare What the Body Does to Selatogrel and the Effect of Selatogrel in Chinese Adults With Chronic Coronary Syndrome

RecruitingNCT07615868

Viatris Innovation GmbHChronic Coronary Syndrome

Start: 2026-06-22End: 2026-10-01Target: 20Updated: 2026-07-14

Phase 2

A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Coronary Artery Disease

CompletedNCT03384966

Viatris Innovation GmbHStable Coronary Artery Disease

Start: 2018-01-24End: 2018-09-18Updated: 2026-07-29

Phase 3

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

Enrolling by invitationNCT04957719

Viatris Innovation GmbHAcute Myocardial Infarction

Start: 2021-08-14End: 2027-07-01Target: 25000Updated: 2026-07-23

Related Papers

Transition from Syringe to Autoinjector Based on Bridging Pharmacokinetics and Pharmacodynamics of the P2Y<sub>12</sub> Receptor Antagonist Selatogrel in Healthy Subjects.

2021-12-283 citations

Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes

European Heart Journal2019-10-2575 citations