Seladelpar
Sponsors
Gilead Sciences, University of California, San Diego
Conditions
Compensated CirrhosisHepatic ImpairmentIschemic CholangiopathyLiver Transplant; ComplicationsNASH - Nonalcoholic SteatohepatitisPrimary Biliary CholangitisPrimary Sclerosing Cholangitis
Phase 1
Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Seladelpar in Subjects With Hepatic Impairment and Healthy Subjects
CompletedNCT03369002
Start: 2017-11-27End: 2018-05-15Updated: 2018-05-18
An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)
CompletedNCT04950764
Start: 2021-11-16End: 2025-02-27Updated: 2026-05-04
Phase 2
A Study to Evaluate Seladelpar in Subjects With Nonalcoholic Steatohepatitis (NASH)
TerminatedNCT03551522
Start: 2018-04-30End: 2020-08-10Updated: 2022-09-15
A Study to Evaluate the Safety, and Tolerability, and Efficacy of Seladelpar in Patients With PSC
TerminatedNCT04024813
Start: 2019-11-12End: 2020-01-09Updated: 2025-01-16
Seladelpar in Adult Liver Transplant Recipients With Ischemic Cholangiopathy (SELIC).
Not yet recruitingNCT07305363
Start: 2026-05-01End: 2027-12-01Target: 10Updated: 2026-04-09