Second-line Antidepressants

DRUG2 trials

Sponsors

Dr. Inge Winter

Conditions

Bipolar DepressionMajor Depressive DisorderSchizophrenia and Related DisordersTreatment Resistant Depression

Phase 3

Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure

RecruitingNCT05603104

Dr. Inge WinterBipolar Depression, Major Depressive Disorder, Schizophrenia and Related Disorders

Start: 2025-04-27End: 2028-06-30Target: 1254Updated: 2026-01-22

The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.

RecruitingNCT05973851

Dr. Inge WinterMajor Depressive Disorder, Treatment Resistant Depression

Start: 2024-08-31End: 2028-06-30Target: 418Updated: 2025-09-26

Related Papers

INTENSIFY—a randomized, controlled trial to investigate the effect of an early intensified pharmacological treatment for major psychiatric disorders after treatment failure in the current episode: a study protocol

Trials2026-08-05

Cross-sectional analysis of ongoing clinical trials involving lamotrigine for mental disorders: Insights from ClinicalTrials.gov and the EU clinical trials.

2025-12-04