Scemblix 20 mg film-coated tablets
Sponsors
Novartis Pharma AG, Novartis Farma S.p.A., Grupo Espanol De Leucemia Mieloide Cronica (GELMC)
Conditions
Chronic Myelogenous Leukemia in chronic phase (CML-CP)Chronic Myeloid LeukemiaChronic myeloid leukemiapreviously treated with imatinib and have not achieved deep molecular response
Phase 2
A phase II, single-arm study of de-escalation and treatment-free remission in patients with chronic myeloid leukemia treated with nilotinib in first-line therapy followed by a second attempt after nilotinib and asciminib combination: DANTE study
CompletedCTIS2024-516122-66-00
Start: 2019-01-18End: 2025-10-15Target: 170Updated: 2025-07-09
A phase 2, multi-center, open-label, randomized study of oral asciminib added to imatinib versus continued imatinib versus switch to nilotinib in patients with CML-CP who have been previously treated with imatinib and have not achieved deep molecular response
CompletedCTIS2024-515040-23-00
Start: 2018-11-26End: 2025-02-26Target: 37Updated: 2025-02-18
Safety and efficacy of treatment combination with ponatinib and asciminib in chronic myeloid leukemia patients resistant to ponatinib and/or asciminib
Not yet recruitingCTIS2025-521126-15-00
Target: 30Updated: 2026-06-01