SB-007
Sponsors
Splicebio S.L., Splice Bio
Conditions
Stargardt DiseaseStargardt Macular DegenerationStargardt Macular Dystrophy
Phase 1
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)
RecruitingNCT06942572
Start: 2025-02-11End: 2028-12-31Target: 57Updated: 2025-04-29
A Phase 1/2, First-in-Human, Open-label, Assessor-Masked, Randomized, Controlled, Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects with Stargardt Disease (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ATP Binding Cassette Subfamily A Member 4 (ABCA4) Gene (ASTRA).
Not yet recruitingCTIS2024-519535-42-00
Target: 10Updated: 2026-01-23