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Saxagliptin 5mg

DRUG6 trials

Sponsors

AstraZeneca, Sabyasachi Sen, University of Pisa, Eric Grouzmann, Ain Shams University

Conditions

Cardiovascular DiseasesDiabetes Mellitus, Type 2Drug InteractionErectile Dysfunction With Diabetes MellitusPhysical ActivitySecretion; CatecholamineSympathetic Nervous SystemType 2 Diabetes Mellitus

Early Phase 1

Neuropeptide Y and Sympathovagal Balance
CompletedNCT03933787
Eric GrouzmannPhysical Activity, Secretion; Catecholamine, Sympathetic Nervous System
Start: 2018-06-05End: 2019-04-15Updated: 2019-05-01

Phase 2

Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.
CompletedNCT03714594
University of PisaType2 Diabetes Mellitus
Start: 2018-07-24End: 2022-08-31Updated: 2022-11-08

Phase 3

Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control
CompletedNCT02104804
AstraZenecaType 2 Diabetes Mellitus
Start: 2014-05-07End: 2016-02-26Updated: 2017-10-02

Phase 4

Effect of Saxagliptin and Dapagliflozin on Endothelial Progenitor Cell in Patients With Type 2 Diabetes Mellitus
TerminatedNCT03660683
Sabyasachi SenCardiovascular Diseases, Diabetes Mellitus, Type 2
Start: 2018-10-22End: 2021-12-10Updated: 2023-06-05
Tubular Markers in Response to Saxagliptin Therapy
CompletedNCT04521049
Beni-Suef UniversityDiabetes Mellitus, Type 2
Start: 2019-03-01End: 2020-04-01Updated: 2020-08-20

Unknown Phase

Evaluation of Drug Interactions of Saxagliptin With Sildenafil in Healthy Volunteers
NCT04170790
Ain Shams UniversityDiabetes Mellitus, Type 2, Drug Interaction, Erectile Dysfunction With Diabetes Mellitus
Start: 2019-12-01End: 2020-01-30Target: 18Updated: 2019-11-20

Related Papers

Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM) subjects: a randomized trial
Stem Cell Research & Therapy2025-01-263 citations
Evaluation of drug interactions of saxagliptin with sildenafil in healthy volunteers
European Journal of Clinical Pharmacology2022-10-105 citations
Saxagliptin add‐on therapy in Chinese patients with type 2 diabetes inadequately controlled by insulin with or without metformin: Results from the SUPER study, a randomized, double‐blind, placebo‐controlled trial
Diabetes Obesity and Metabolism2017-11-1612 citations