SARS-CoV-2 convalescent plasma

BIOLOGICAL5 trials

Sponsors

Johns Hopkins University, Joakim Dillner, University Hospital, Geneva

Conditions

COVID-19Covid19Immuno-DeficiencyOld Age; DebilitySARS-CoV 2

Phase 1

Convalescent Plasma for Treatment of COVID-19: An Exploratory Dose Identifying Study

CompletedNCT04384497

Joakim DillnerCOVID-19

Start: 2020-05-07End: 2020-12-01Updated: 2021-12-03

Convalescent Plasma as Treatment for Acute Coronavirus Disease (COVID-19)

CompletedNCT04390178

Joakim DillnerCOVID-19

Start: 2020-04-10End: 2020-12-31Updated: 2021-12-16

Phase 2

Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

CompletedNCT04373460

Johns Hopkins UniversitySARS-CoV 2

Start: 2020-06-03End: 2022-12-14Updated: 2023-06-02

Convalescent Plasma for Treatment of COVID-19

CompletedNCT04649879

Joakim DillnerCovid19

Start: 2020-12-03End: 2022-01-26Updated: 2022-02-09

Phase 3

Preemptive Use of Convalescent Plasma for High-risk Patients With COVID-19

University Hospital, GenevaCovid19, Immuno-Deficiency, Old Age; Debility

Start: 2021-04-08End: 2021-12-31Target: 100Updated: 2021-04-08

Related Papers

Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial

JCI Insight2024-03-1411 citations

Symptom Duration and Resolution With Early Outpatient Treatment of Convalescent Plasma for Coronavirus Disease 2019: A Randomized Trial

The Journal of Infectious Diseases2023-01-312 citations

Early Outpatient Treatment for Covid-19 with Convalescent Plasma

New England Journal of Medicine2022-03-30264 citations

Pharmacokinetics of high-titer anti–SARS-CoV-2 human convalescent plasma in high-risk children

JCI Insight2021-12-0224 citations

Convalescent plasma for treatment of COVID-19: study protocol for an open randomised controlled trial in Sweden

BMJ Open2021-12-012 citations

Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults.

2021-03-2013 citations