FindTrial
Sign In

SAPIEN 3 THV

DEVICE4 trials

Sponsors

Cardiovascular Research Foundation, New York, Edwards Lifesciences

Conditions

Aortic StenosisAortic Valve StenosisComplex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve DegenerationPulmonary Valve InsufficiencyPulmonary Valve; Obstruction

Unknown Phase

Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)
Active, not recruitingNCT02661451
Cardiovascular Research Foundation, New YorkAortic Valve Stenosis
Start: 2016-09-30End: 2025-02-28Updated: 2024-11-27
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis
Active, not recruitingNCT02675114
Edwards LifesciencesAortic Stenosis
Start: 2016-03-31End: 2029-12-31Updated: 2026-01-14
COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction
RecruitingNCT02744677
Edwards LifesciencesComplex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Degeneration +1
Start: 2016-07-05End: 2031-06-01Target: 108Updated: 2026-03-06
COMPASSION S3 Post-Approval Study
Active, not recruitingNCT04860765
Edwards LifesciencesComplex Congenital Heart Defect, Dysfunctional RVOT Conduit, Pulmonary Valve Degeneration +2
Start: 2021-04-13End: 2030-08-01Updated: 2026-02-03

Related Papers

Five-Year Outcomes for Patients With RVOT Dysfunction Treated With the SAPIEN 3 Transcatheter Heart Valve: A Pooled Analysis From the COMPASSION S3 Trial.
2026-03-26
Transcatheter or Surgical Aortic-Valve Replacement in Low-Risk Patients at 7 Years.
2025-10-27
5-Year Echocardiographic Results of Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients.
2025-04-162 citations
Transcatheter aortic valve implantation versus surgical aortic valve replacement in severe aortic stenosis patients at low surgical mortality risk: a cost-effectiveness analysis in Belgium.
2023-11-2118 citations
Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years
New England Journal of Medicine2023-10-24491 citations
Cardiac Damage and Quality of Life After Aortic Valve Replacement in the PARTNER Trials.
2023-02-0140 citations
Cost-Effectiveness of SAPIEN 3 Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in German Severe Aortic Stenosis Patients at Low Surgical Mortality Risk.
2023-01-0913 citations
Congenital Pulmonic Valve Dysfunction Treated With SAPIEN 3 Transcatheter Heart Valve (from the COMPASSION S3 Trial).
2023-01-049 citations
Evolution and Prognostic Impact of Cardiac Damage After Aortic Valve Replacement.
2022-05-17113 citations
Impact of Predilation During Transcatheter Aortic Valve Replacement: Insights From the PARTNER 3 Trial
Circulation Cardiovascular Interventions2021-06-1812 citations
Utilization, Costs, and Outcomes of Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement
Circulation Cardiovascular Interventions2021-06-1622 citations
Outcomes 2 Years After Transcatheter Aortic Valve Replacement in Patients at Low Surgical Risk.
2021-03-01218 citations
Pathways Towards Lean TAVR
Structural Heart2020-05-133 citations
Echocardiographic Results of Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients
Circulation2020-04-10132 citations
Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients
New England Journal of Medicine2019-03-164593 citations
Moderate Aortic Stenosis and Reduced Left Ventricular Ejection Fraction: Current Evidence and Challenges Ahead.
2018-08-178 citations
Aortic Stenosis at the Crossroads
Structural Heart2018-07-23
Trials Testing the Value of Imaging Use in Valve Disease and in Transcatheter Valvular Interventions.
2017-03-014 citations
Rationale and design of the Transcatheter Aortic Valve Replacement to UNload the Left ventricle in patients with ADvanced heart failure (TAVR UNLOAD) trial.
2016-08-26132 citations