Saphnelo 300 mg concentrate for solution for infusion
Sponsors
AstraZeneca AB, Astrazeneca AB, Centre Hospitalier Universitaire De Bordeaux, Universitair Medisch Centrum Groningen, Medical University Of Vienna
Conditions
Active Proliferative Lupus NephritisModerate to Severe Active Systemic Lupus ErythematosusPatient with non-segmental (symmetrical) vitiligo with a body surface area involved >5% excluding hands and feetSjogren's diseasecutaneous lupus erythematosus
Phase 2
Efficacy and tolerance of the association of ANIFROLUMAB (300mg) IV every four weeks and phototherapy versus phototherapy in adults with progressive vitiligo: a randomized double blind prospective, non comparative Proof of Concept phase II study - VITANI
RecruitingCTIS2024-512041-17-00
Start: 2023-11-27Target: 48Updated: 2026-01-13
ANISE-II; ANIfrolumab treatment for 24 weeks in patients with primary Sjögren’s syndrome – Efficacy and safety assessment in a randomized, double-blind, placebo-controlled phase-IIa proof-of-concept trial
CompletedCTIS2024-516770-29-00
Start: 2022-10-09End: 2025-08-21Target: 30Updated: 2024-11-01
Phase 3
A Phase III, Randomized, Double-blind, Parallel-group, Placebo controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of IV Anifrolumab in Pediatric Participants 5 to < 18 Years of Age with Moderate to Severe Active Systemic Lupus Erythematosus While on Background Standard of Care Therapy
RecruitingCTIS2022-502289-25-00
Start: 2024-08-28Target: 20Updated: 2025-09-10
A Multicenter Randomized Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Anifrolumab in Adult Patients with Active Proliferative Lupus Nephritis
Active, not recruitingCTIS2023-506359-68-00
Start: 2022-04-08Target: 69Updated: 2025-05-15